Developing and testing methods for deriving condition-specific preference-based measures from existing measures (COSMeQ)

The COSMeQ project reviewed, developed and tested methods for deriving condition-specific preference-based measures (CSPBM) to generate QALYs from existing measures. The project examined issues such as:

• the methodological challenges of developing a preference-based measure for common mental health problems
• whether labelling the underlying condition affects utility values
• comparing the performance of condition-specific measures to generic measures and to the non-preference-based measure it was derived from
• the adaptation of measures to be able to capture co-morbidities and side-effects of treatment through adding on a generic dimension to a CSPBM

The COSMeQ study was funded by MRC-NIHR Methodology Research Programme, project number 06/97/04.

Relevant Publications

• Brazier J, Tsuchiya A. Preference-based condition-specific measures of health: What happens to cross programme comparability? Health Economics 2010;19(2):125-9.
• Brazier J, Rowen D, Tsuchiya A, et al. The impact of adding a generic dimension to a condition-specific preference-based measure. Health Economics and Decision Science Discussion Paper, University of Sheffield 2010 (Forthcoming).
• Mavranezouli I, Brazier J, Young A, Barkham M. Using Rasch analysis to form plausible health states amenable to valuation: the development of the CORE-6D from a measure of common mental health problems (CORE-OM). Quality of Life Research 2010;In press.
• Rowen D, Brazier J, Tsuchiya A, et al. It's all in the name, or is it? The impact of labelling on health state values. Health Economics and Decision Science Discussion Paper, University of Sheffield 2010.
• Rowen D, Brazier J, Young T, et al. Deriving a preference-based measure for cancer using the EORTC QLQ-C30. Health Economics and Decision Science Discussion Paper, University of Sheffield 2010.
• Rowen D, Brazier J, Yang Y, et al. A review of studies developing preference-based measures of quality of life from condition specific measures. Health Economics and Decision Science Discussion Paper, University of Sheffield 2010 (Forthcoming).
• Rowen D, Brazier J, Tsuchiya A, et al. It's all in the name, or is it? The impact of labelling on health state values. Health Economics and Decision Science Discussion Paper, University of Sheffield 2010.
• Rowen D, Young, T Brazier J, et al. Comparison of generic, condition-specific and mapped health state utility values. Health Economics and Decision Science Discussion Paper, University of Sheffield 2010 (Forthcoming).
• Young T, Rowen D, Norquist J, Brazier J. Developing preference-based health measures: using Rasch analysis to generate health state values. Quality of Life Research 2010;19:907-17.

HEDS Discussion Paper Series 2010

Further Information

If you would like further information about this work, please contact d.rowen@sheffield.ac.uk