The University of Sheffield
Department of Materials Science and Engineering

Professor Sheila MacNeil

Prof S Macneil

BSc, PhD
Professor of Tissue Engineering
Director, Interdisciplinary Programmes, Faculty of Engineering

Address:
The Kroto Research Institute
North Campus
University of Sheffield
Broad Lane
Sheffield
S3 7HQ

Telephone: +44 (0) 114 222 5995
Fax: +44 (0) 114 222 5943

Email: s.macneil@sheffield.ac.uk

Sheila MacNeil is Professor of Tissue Engineering in the Department of Materials Science and Engineering, joining the department in 2000. She has an undergraduate degree in physiology from the University of Aberdeen and a doctorate on the endocrinology of manic depression from the Medical School of the University of Sheffield.

She is Director of the Interdisciplinary Programmes Office for the Faculty of Engineering (from February 2010) and Director of the Faculty degree of Bioengineering (launched September 2010

She has previously been Deputy Director of the Kroto Research Institute (from 2005 to 2009) and Director of the University Centre for Biomaterials and Tissue Engineering from 2002 to 2009, promoting interdisciplinary research between engineering, physical sciences and life sciences (see www.cbte.group.shef.ac.uk).  She was also a founding Director of the University of Sheffield spin-out company, CellTran Limited from 2000 to 2007. She was the Sheffield lead for an EPSRC Doctoral Training Centre in Tissue Engineering and Regenerative Medicine (a DTC held between three Universities, Leeds, Sheffield and York) from 2008 to 2011.

Research interests

Her research focuses on developing tissue engineering which will benefit patients, alongside fundamental work to develop new understanding and tools in the area of tissue engineering. Her primary research interests are in tissue engineering of soft tissues – skin, oral mucosa, urethra and cornea, with a strong focus on translating research for clinical benefit. Her group have a long history of working with clinical NHS colleagues using tissue engineered skin to benefit burns patients (from 1992) and more recently patients with chronic ulcers (2004) and patients requiring reconstructive surgery of the urethra (from 2007). She has developed the product Myskin™ which was clinically evaluated and developed commercially and has been available in the UK for patients with extensive skin loss due to burns injuries and to chronic non-healing ulcers from 2005, currently available through the company Altrika. Additionally she has developed 3D tissue engineered models used to study a wide range of normal and abnormal conditions spanning wound healing, skin contracture, pigmentation, melanoma invasion, angiogenesis, bacterial infection and skin sensitisation.

Key projects

Professional activities and recognition

Key publications

Publications 2005 onwards (pdf, 75kb)

Research group

Postdoctoral Research Assistants
Dr Anthony Bullock
Dr Pallavi Deshpande
Dr Farshid Sefat
Dr Ilida Ortega
Dr Luciana Bostan
Dr Joey Shepherd

Clinical Research Fellows

Mr Nadir Osman
Ms Naside Mangir
Mr Chris Hillary

PhD Students

Mrs Munira Shahbuddin (co-supervised with Chemistry)
Miss Annika Clifton (co-supervised with Chemistry)
Miss Amanda Harvey (co-supervised with Chemistry)
Miss Enas Hassan (co-supervised with Chemistry)
Mr Sabiniano Roman (co-supervised with Mr Chris Chapple, Consultant Urologist, Royal Hallamshire Hospital).
Miss Ceyla Yorucu (co-supervised with Dr I Rehman)
Mr Christopher Tse (co-supervised with Dr P Smith & Prof J Haycock)
Mr Daniel Cozens (co-supervised with the Medical School)
Miss Giulia Gigliobianco (co-supervised with Dr CK Chong)
Miss Jenny Ventress (co-supervised with the Medical School)
Mr Joseph Boadi (co-supervised with Dr S Matcher)
Miss Lindsey Dew (co-supervised with Drs CK Chong and F Claeyssens)
Mr Sam Beckett (co-supervised with Dr S Matcher)
Mr Samand Pashneh-Tala (co-supervised with Dr CK Chong)
Miss Sasima Puwanun (co-supervised with Dr G Reilly)

Technical Staff

Mr Mark Wagner
Mr Robert Dickinson
Miss Claire Johnson

Research centres

Centre for Biomaterials and Tissue Engineering

Teaching

MAT206 – 10 credits – Physiology of Neural and Endocrine System
MAT300 – 20 credits – Tissue Engineering
FCE101 - 20 credits - An Introduction to Bioengineering.
FCE201 - 10 credits - Advanced Bioengineering Topics

Supervision of 2 to 3 honours project students per year for 30 credit BEng (MAT356) and 60 credit (MAT404) research projects.

Administration

Director of Interdisciplinary Programmes, Faculty of Engineering
Course Director, Bioengineering
Chair of Management Committee for BBSRC Doctoral Training Award (studentships held jointly between the Kroto Research Institute and Faculty of Medicine, Sheffield).