Professor David I. Strutt
Senior Research Fellow/Professor
Department of Biomedical Science The University of Sheffield Western Bank Sheffield S10 2TN United Kingdom
email : d.strutt@sheffield.ac.uk
Room: D36 Firth Court
Telephone: +44 (0) 114 222 2372
Research Interests
Cell polarisation is a fundamental process in the development of complex multicellular organisms. We are interested in how such polarisation is coordinated and maintained during development, with a primary interest in the roles of the Frizzled sevenpass transmembrane receptor.
Read more (link to the Centre for Developmental and Biomedical Genetics)
History
- 2005: Professor of Developmental Genetics
- 2003-present: Wellcome Senior Fellow in Basic Biomedical Science, University of Sheffield
- 1998-2003: Lister Institute-Jenner Research Fellow, University of Sheffield
- 1997-1998: Lecturer, University of Sheffield
- 1993-1997: Postdoctoral Fellow, European Molecular Biology Laboratory, Heidelberg
- 1991-1993: Postdoctoral Fellow, Department of Anatomy, University of Cambridge
- 1988-1991: PhD, Department of Anatomy, University of Cambridge
- 1985-1988: BA Natural Sciences, University of Cambridge
Activities and Distinctions
- Wellcome Trust Senior Fellow in Basic Biomedical Science
- Editorial board of Current Biology
Funding
Recent Publications
- Strutt D.
The planar polarity pathway. Curr Biol. 2008;18(19):R898-902. - Strutt H, Strutt D.
Differential stability of flamingo protein complexes underlies the establishment of planar polarity. Curr Biol. 2008;18(20):1555-64. - Strutt D, Warrington SJ.
Planar polarity genes in the Drosophila wing regulate the localisation of the FH3-domain protein Multiple Wing Hairs to control the site of hair production. Development. 2008;135(18):3103-11. - Brunk K, Vernay B, Griffith E, Reynolds NL, Strutt D, Ingham PW, Jackson AP.
Microcephalin coordinates mitosis in the syncytial Drosophila embryo. J Cell Sci. 2007;120(Pt 20):3578-88. - Bastock, R. and Strutt, D. (2007)
The planar polarity pathway promotes coordinated cell migration during Drosophila oogenesis. Development 134:3055-3064. - Strutt, D. and Strutt, H. (2007)
Differential activities of the core planar polarity proteins during Drosophila wing patterning. Developmental Biology 302:181-194. - Strutt, H., Price, M.A., and Strutt, D. (2006)
Planar polarity is positively regulated by casein kinase I epsilon in Drosophila. Current Biology 16:1329-1336.
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