Professor Steve Goodacre MB, ChB, MRCP, DipIMC, FRCEM, MSc, PhD

stevegoodacreTel: (+44) (0)114 222 0842
Email: s.goodacre@sheffield.ac.uk

Room: 3023 Regent Court


Biography

I am a clinical academic in emergency medicine and researcher in emergency care. I am a National Institute for Health Research Senior Investigator and am currently Chair of the NIHR Health Technology Assessment Clinical Evaluation and Trials Board.

Research Interests

My research interests are clinical trials in emergency medicine, economic analysis, the organisation of emergency care and methods for evaluating the quality of emergency care.

Teaching Interests

My teaching interests are critical appraisal of the scientific literature, promoting evidence-based health care, advanced trauma life support (ATLS) and diagnosis of acute chest pain and deep vein thrombosis.

I am interested in supervising students undertaking research in emergency care, such as evaluation of health technologies, changes to service delivery, methods to improve decision-making and methods for evaluating the quality of emergency care.

I co-ordinate the Promoting Evidence Based Health Care optional module on the Master in Public Health and Master in Clinical Research courses.

Professional activities

Chair, NIHR Health Technology Assessment Clinical Evaluation and Trials Board

NIHR Senior Investigator

Consulting Editor, Annals of Emergency Medicine

Chair, ScHARR Research Committee

Current and Recent Projects

Chief Investigator

DiPEP: Diagnosis of Pulmonary Embolism in Pregnancy. Funded by the NIHR Health Technology Assessment R&D Programme, £688,196.

The PAINTED study: Pandemic Influenza Triage in the Emergency Department. Funded by the NIHR Health Technology Assessment R&D Programme, £151,174.

Evidence synthesis of prehospital Non-invasive Ventilation. Funded by the NIHR Health Technology Assessment R&D Programme, £133,895.

The 3Mg Trial: A randomised controlled trial of nebulised versus IV magnesium sulphate versus placebo for acute severe asthma. Funded by the NIHR Health Technology Assessment R&D Programme, £1,727,163.

DAVROS: Development and Validation of Risk-adjusted Outcomes for Systems of emergency care. Funded by the Medical Research Council, £951,554.

Diagnostic strategies for suspected acute coronary syndrome. Funded by the NIHR Health Technology Assessment R&D Programme, £176,928.

Emergency Planning in Health Care: Scoping study of the international literature, local information resources and key stakeholders. Funded by the NIHR Service Delivery and Organisation R&D Programme, £152,304.

The RATPAC Trial: Randomised Assessment of Treatment using Panel Assay of Cardiac markers. Funded by the NIHR Health Technology Assessment R&D Programme, £795,042.

Co-investigator

EDARA: Evaluating the Diversion of Alcohol-Related Attendances. Chief Investigator Simon Moore (University of Cardiff). Funded by the NIHR Health Services & Delivery Research R&D programme, £739,381

Safer care patient-centred checklist. Chief Investigator Mike Clancy (Southampton General Hospital). Funded by the Health Foundation, £73,690.

SAFE: Seizure first Aid training For Epilepsy . Chief Investigator Adam Noble (University of Liverpool). Funded by the NIHR Health Service & Delivery R&D Programme, £424,127

The RAPID-CTCA trial: Rapid Assessment of Potential Ischaemic Heart Disease with CT coronary angiography. Chief Investigator Alasdair Gray (Royal Infirmary of Edinburgh). Funded by the NIHR Health Technology Assessment R&D Programme, £2,058,508.

SPRAINED: Synthesising a clinical Prognostic Rule for Ankle INjuries in the Emergency Department. Chief Investigator Sallie Lamb (University of Oxford). Funded by the NIHR Health Technology Assessment R&D Programme, £820,997.

Development and validation of the 4AT: a new triage tool for delirium. Chief Investigator Alasdair MacLullich (Royal Infirmary of Edinburgh). Funded by the NIHR Health Technology Assessment R&D Programme, £827,431.

Lab2Go: Demonstrating Minicare, a miniaturised biophotonics platform for fast and lab-equivalent point-of-care diagnostics. Funded by the EU ICT Policy Support Programme, €1,915,000.

Predictors of preventable unplanned admission rates. Chief Investigator Alicia O'Cathain. Funded by NIHR Service Delivery and Organisation, £278,997.

Developing outcome measures for prehospital care. Chief Investigator Janette Turner. Funded by NIHR Programme Grant, £1,286,660.

The AHEAD Study: Managing anticoagulated patients who suffer head injury. Chief Investigator Suzanne Mason. Funded by the NIHR Research for Patient Benefit Programme, £248,550.

Head Injury Transportation Straight to Neurosurgery (HITS-NS). Chief Investigator Fiona Lecky. Funded by the NIHR Health Technology Assessment R&D Programme, £539,573.

Can an ‘accelerated pathway’ reduce admissions for chest pain in New Zealand? Chief Investigator Martin Than (Christcurch Hospital, New Zealand). Funded by Research for New Zealand Health Delivery, NZ$899,710.

RATPAC Contemporary Biomarker Evaluation. Chief Investigator Paul Collinson (St George's Hospital). Funded by the NIHR Health Technology Assessment R&D Programme, £243,482.

Key Publications

Thokala P, Goodacre S, Ward M, Penn-Ashman J, Perkins GD. Cost-effectiveness of Out-of-Hospital Continuous Positive Airway Pressure (CPAP) for Acute Respiratory Failure. Ann Emerg Med 2015;65:556-563.

Goodacre S, Cohen J, Bradburn M, Gray A, Benger J, Coats T, on behalf of the 3Mg Research Team. Intravenous or nebulised magnesium sulphate versus standard therapy for severe acute asthma (3Mg trial): a double-blind, randomised controlled trial. Lancet Respir Med 2013;1:293-300.

Goodacre S, Wilson R, Shephard N, Nicholl J on behalf of the DAVROS Research Team. Derivation and validation of a risk adjustment model for predicting seven day mortality in emergency medical admissions: mixed prospective and retrospective cohort study. BMJ 2012;344:e2904

Goodacre S, Bradburn M, Cross E, Collinson P, Gray A, Hall AS on behalf of the RATPAC Research Team. The Randomised Assessment of Treatment using Panel Assay of Cardiac Markers (RATPAC) trial: a randomised controlled trial of point-of-care cardiac markers in the emergency department. Heart 2011;97:190-196.

Arnold J, Goodacre S, Bath P, Price J. Randomised controlled trial of information sheets for patients with acute chest pain. BMJ 2009;338:b541.

Gray A, Goodacre S, Newby D, Masson M, Sampson F, Nicholl J on behalf of the 3CPO triallists. Effectiveness of non invasive ventilation in patients with acute severe cardiogenic pulmonary oedema. New Engl J Med 2008;359:142-51.

Goodacre S, Cross E, Lewis C, Nicholl J & Capewell S, on behalf of the ESCAPE Research Team. The ESCAPE cluster randomised trial: Effectiveness and Safety of Chest pain Assessment to Prevent Emergency admissions. BMJ 2007;335:659-662.

Goodacre S, Sutton AJ and Sampson F. The value of clinical assessment in the diagnosis of deep vein thrombosis: a meta-analysis. Ann Intern Med 2005;143:129-139.

Goodacre S, Nicholl J, Dixon S, Cross E, Angelini K, Arnold J, Revill S, Locker T, Capewell S, Quinney D, Campbell S & Morris F. Randomised controlled trial and economic evaluation of a chest pain observation unit compared with routine care. BMJ 2004;328:254-7.

Section

Steve is based in the section of Health Services Research

Address: Health Services Research, School of Health and Related Research (ScHARR), University of Sheffield, Regent Court, 30  Regent Street, Sheffield S1 4DA

Contact Number: 0114 222 0834 Contact Fax: 0114222 0749