Mike Bradburn MSc
Medical Statistician
Clinical Trials Research Unit
ScHARR
University of Sheffield
Regents Court, 30 Regent Street
Sheffield
S1 4DA
Tel: +44 (0)114 22 20706
Fax: +44 (0)114 22 20870
email : m.bradburn@sheffield.ac.uk
Biography
I joined the CTRU in 2007, having previously worked as a statistician at Cancer Research UK and PAREXEL International. My work is centred around the application of statistical methodology to medical research, primarily clinical trials.
Research interests
Mr primary interest is the implementation of Good Clinical Practice into NHS/academic funded clinical trials. My main areas of methodological interest are meta-analysis and survival analysis.
Teaching interests
I teach statistical and trial-based methods on the following ScHARR course modules:
- HAR6035 Introduction to Statistics and Critical Appraisal
- HAR6036 Application of Statistics
- HAR6240 Health Services Research Methods
- MAS6062 Bayesian Inference & Further Clinical Trials
Professional activities
- Reviewer for various journals and funding bodies
- Trial steering committee member for three studies
Current projects
- TABUL -- Temporal artery biopsy vs ultrasound in diagnosis of giant cell arteritis. Funded by NIHR HTA
- 3Mg -- Magnesium sulphate for treatment of severe acute asthma. Funded by NIHR HTA
- REPOSE -- Relative Effectiveness of Pumps Over MDI and Structured Education.. Funded by NIHR HTA
- CoPE -- Corn Plaster Evaluation Trial: The long term effectiveness of 40% salicylic acid plasters on corns. Funded by NIHR RfPB
- DiPALS -- A Randomised Controlled Trial in patients with Respiratory Muscle Weakness due to Motor Neurone Disease of the NeuRx RA/4 Diaphragm Pacing Trial. Funded by NIHR HTA
- Secondary Analysis of Community Rehabilitation and Intermediate Care - an Information Resource. Funded by NIHR SDO
Key publications
- Bradburn M, Goodacre SW, Fitzgerald P, Coats T, Gray A, Hassan T, Humphrey J, Kendall J, Smith J, Collinson P; On behalf of the RATPAC Research Team. Interhospital variation in the RATPAC Trial (Randomised Assessment of Treatment using Panel Assay of Cardiac markers). Emergency Medicine Journal 2012;29:233-238
- Goodacre SW, Bradburn M, Fitzgerald P, Cross E, Collinson P, Gray A, Hall A. The RATPAC (Randomised Assessment of Treatment using Panel Assay of Cardiac markers) trial: a randomised controlled trial of point-of-care cardiac markers in the emergency department. Health Technology Assessment 2011;15(23):1-108.
- Houghton S, Saxon D, Bradburn M, Ricketts T, Hardy G. The effectiveness of routinely delivered cognitive behavioural therapy for obsessive compulsive disorder: a benchmarking study. British Journal of Clinical Psychology 2010 ; 49(4): 473-489
- Harris R, Bradburn M, Deeks J, Harbord R, Altman D, Sterne J. Metan: fixed- and random-effects meta-analysis. Stata Journal 2008; 8(1): 3-28.
- Bradburn MJ, Deeks JJ, Berlin JA, Localio AR. Much ado about nothing: a comparison of the performance of meta-analytical methods with rare events. Statistics in Medicine 2007; 26: 53-77.