Dawn Teare BSc, MSc, PhD
Senior Lecturer in Genetic Epidemiology
Address:
Design, Trials & Statistics
School of Health and Related Research (ScHARR)
University of Sheffield
Regent Court, 30 Regent Street
Sheffield S1 4DA
Tel: (+44) (0)114 2226398
Fax: (+44) (0)114 2220749
Email: m.d.teare@sheffield.ac.uk
Room: 3037
Biography
I graduated with a BSc (Hons) in Statistics and Computer Science, followed by an MSc in Statistics from the University of Sheffield. On completion of my PhD entitled `Modelling familial cancer risk´ and awarded by the University of Manchester I accepted a post-doctoral position at the University of Cambridge. In 2001 I returned to Sheffield to join the Mathematical Modelling and Genetic Epidemiology Group based at the Medical School. In 2009 I moved to the Health Services Research section in ScHARR.
Research Interests
• Genetic epidemiology
• Population genetics
• The application of statistics in experimental and medical research
Teaching Interests
My teaching activities include:
• Module co-ordinator for HAR6039: Statistics for clinical research (MSc in Clinical Research)
• Contribute to PAS6061: Epidemiology (MSc in Statistics with medical applications)
• Contribute to MED6008: Introduction to statistics (MSc in Molecular Medicine.)
• Deliver one-day courses on statistics to Specialist Registrars.
Professional Activities
• Member of Royal Statistical Society Medical Section
• Member of Yorkshire and Humberside NIHR-RfPB Committee
Current Projects
I am a co-investigator in two research projects, AHEAD and ReSoLuCENT. The AHEAD study has been funded by NIHR-RfPB and runs for 24 months from 2011. This is a cohort study to investigate the management of anticoagulated patients who suffer head injury. The ReSoLuCENT study (Resource for the Study of Lung Cancer Epidemiology in North Trent), is a family based study of early onset lung cancer. We have now secured a further two years funding (Weston Park Hospital Trustees) to recruit up to 1000 lung cancer cases and controls.
Key Publications
1. Ala A, Jones J, Bradley M, Bhala N, Rahman A, Peck R, Teare M.D., Gleeson D. (2012) Familial predisposition to alcoholic liver disease: a case control study. ( European Journal of Gastroenterology & Hepatology in press).
2. Dexter LJ, Teare MD, Dexter M, Siriwardena AN, Read RC. (2012) Strategies to increase influenza vaccination rates: outcomes of a nationwide cross-sectional survey of UK general practice. BMJ Open DOI: 10.1136/bmjopen-2011-000851
3. Coté ML, Liu M, Bonassi S, Neri M, Schwartz AG, Christiani DC, .., Teare MD, .., , Etzel CJ, Hung RJ, Increased risk of lung cancer in individuals with a family history of the disease: A pooled analysis from the International Lung Cancer Consortium, European Journal of Cancer, Available online 19 March 2012, ISSN 0959-8049, 10.1016/j.ejca.2012.01.038.
4. Teare M.D., Pinyakorn S, Santibanez Koref MF (2011) Comparing methods for mapping cis-acting polymorphisms using allelic expression ratios. PLoS ONE 6: e28636.
5. Truong T, Hung RJ, Amos CI, Wu X, Bickeboller H, Teare MD…et al. (2010) Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium. J Natl Cancer Inst 102: 959-971.
6. Xue X, Teare MD, Holen I, Zhu YM, Woll PJ. (2009) Optimizing the yield and utility of circulating cell-free DNA from plasma and serum. Clin Chim Acta. 404:100-4.
7. Read, RC, Teare MD, et al. (2009). The tumor necrosis factor polymorphism TNF (-308) is associated with susceptibility to meningococcal sepsis, but not with lethality. Critical Care Medicine 37(4): 1237-1243.
8. Gleeson, D., Bradley MP, Jones J, Peck RJ, Bond SK, Teare MD, Duff GW. (2008). Cytokine Gene Polymorphisms in Heavy Drinkers With and Without Decompensated Liver Disease: A Case-Control Study. American Journal of Gastroenterology 103(12): 3039-3046.
Section
I am based in the Design, Trials & Statistics Section