| The Academic Unit of Immunology and Infectious Disease includes clinical and non-clinical scientists who conduct internationally competitive interdisciplinary research in molecular and cellular pathogenesis, immunity, vaccinology and genetics. There is also a strong component of clinical research in infectious disease. |
| The laboratories are housed within F Floor of the Sir Henry Wellcome Research Laboratories. As well as access to the core facilities in proteomics and genomics, there are high quality Cell Biology, Containment Level 2 and Containmnent Level 3 laboratories. The laboratories are adjacent to the Royal Hallamshire Hospital department of Medical Microbiology and to the In-Patient and Out-patient facilities of the Infectious Disease Unit of the Royal Hallamshire Hospital. |
The major research areas include:
- bacterial sensing and manipulation of the host response
- subversion of innate immune defences by pathogens
- regulation of gene expression and DNA replication in bacterial pathogens
- novel adjuvantation of vaccines
- genetics of infectious diseases.
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Pathogen specific research includes:
- Neisseria meningitidis
- Salmonella spp.
- Streptococcus pneumoniae
- Burkholderia spp.
- Chlamydia
- Aeromonas spp.
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The work in the Unit is funded by substantial grant awards from:
- The Medical Research Council
- The Wellcome Trust
- The National Institutes of Health
- BBSRC
- Meningitis UK
- The Meningitis Research Foundation
- Yorkshire Cancer Research
- The Bardhan Trust for Education and Research
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| There is also substantial third leg funding via two bioscience spin-off companies, Asterion and Adjuvantix. |
