The University of Sheffield
Department of Infection and Immunity

Prof A G Wilson MB PhD FRCP DCH

Prof. Gerry Wilson

Academic Unit of Rheumatology
Department of Infection and Immunity
The University of Sheffield Medical School
Beech Hill Road
Sheffield
S10 2RX

Tel: +44 (0)114 271 2232
Fax: +44 (0)114 271 1711
Email: a.g.wilson@sheffield.ac.uk
Secretary - Paula Blackwell
Tel: +44 (0)114 226 1426
Email: paula.blackwell@sheffield.ac.uk

Biography

I graduated in medicine from Queens University Belfast in 1983. I was awarded an ARC Clinical Fellowship for a PhD thesis entitled 'Role of TNF polymorphism in rheumatoid arthritis' which I undertook at the University of Sheffield and successfully completed in 1995. I was subsequently awarded an ARC Copeman Fellowship for research at Stanford University.

I am currently Professor in Rheumatology and Honorary Consultant Rheumatologist.

Research Interests

My research interests include the genetic background of rheumatoid arthritis. Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterised by joint inflammation which frequently leads to joint damage, significant morbidity and increased mortality. The aetiology is multifactorial with a substantial genetic contribution. I am also interested in pharmacogenetics, specifically the identification of biomarkers predictive of response to Methotrexate and anti-TNF.

Teaching Interests

I lecture on the MBChB undergraduate medical course and am the Rheumatology Phase 3b co-ordinator.

Professional Activities

Current Projects

Recent Publications

2013

  1. Knevel, R., A. Krabben, A.G. Wilson, E. Brouwer, M.K. Leijsma, E. Lindqvist, D.P. de Rooy, N.A. Daha, M.P. van der Linden, S. Tsonaka, A. Zhernakova, H.J. Westra, L. Franke, J.J. Houwing-Duistermaat, R.E. Toes, T.W. Huizinga, T. Saxne, and A.H. van der Helm-van Mil. 2013. A genetic variant in granzyme B is associated with progression of joint destruction in rheumatoid arthritis. Arthritis Rheum. 65:582-589. (Abstract) 
  2. de Rooy, D.P., N.G. Yeremenko, A.G. Wilson, R. Knevel, E. Lindqvist, T. Saxne, A. Krabben, M.K. Leijsma, N.A. Daha, S. Tsonaka, A. Zhernakova, J.J. Houwing-Duistermaat, T.W. Huizinga, R.E. Toes, D.L. Baeten, E. Brouwer, and A.H. van der Helm-van Mil. 2013. Genetic studies on components of the Wnt signalling pathway and the severity of joint destruction in rheumatoid arthritis. Ann. Rheum. Dis. 72:769-775. (Abstract) 
  3. Cui, J., E.A. Stahl, S. Saevarsdottir, C. Miceli, D. Diogo, G. Trynka, T. Raj, M.U. Mirkov, H. Canhao, K. Ikari, C. Terao, Y. Okada, S. Wedren, J. Askling, H. Yamanaka, S. Momohara, A. Taniguchi, K. Ohmura, F. Matsuda, T. Mimori, N. Gupta, M. Kuchroo, A.W. Morgan, J.D. Isaacs, A.G. Wilson, K.L. Hyrich, M. Herenius, M.E. Doorenspleet, P.P. Tak, J.B. Crusius, I.E. van der Horst-Bruinsma, G.J. Wolbink, P.L. van Riel, M. van de Laar, H.J. Guchelaar, N.A. Shadick, C.F. Allaart, T.W. Huizinga, R.E. Toes, R.P. Kimberly, S.L. Bridges, Jr., L.A. Criswell, L.W. Moreland, J.E. Fonseca, N. de Vries, B.E. Stranger, P.L. De Jager, S. Raychaudhuri, M.E. Weinblatt, P.K. Gregersen, X. Mariette, A. Barton, L. Padyukov, M.J. Coenen, E.W. Karlson, and R.M. Plenge. 2013. Genome-Wide Association Study and Gene Expression Analysis Identifies CD84 as a Predictor of Response to Etanercept Therapy in Rheumatoid Arthritis. PLoS Genet 9:e1003394. (Abstract)  

2012

  1. Plant, D., Ibrahim, I., Lunt, M., Eyre, S., Flynn, E., Hyrich, K.L., Morgan, A.W., Wilson, A.G., Isaacs, J.D., and Barton, A. Correlation of C-reactive protein haplotypes with serum C-reactive protein level and response to anti-tumour necrosis factor therapy in UK rheumatoid arthritis patients: results from the Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate cohort.  Arthritis Res Ther. 2012 Oct;14(5):R214.  (Abstract)
  2. de Rooy, D.P., Yeremenko, N.G., Wilson, A.G., Knevel, R., Lindqvist, E., Saxne, T., Krabben, A., Leijsma, M.K., Daha, N.A., Tsonaka, S., Zhernakova, S.A., Houwing-Duistermaat, J.J., Huizinga, T.W., Toes, R.E., Baeten, D.L., Brouwer E., van der Helm-van Mil, A.H.  (Abstract)
  3. Maxwell, J.R., Marinou, I., Kue,t K..P, Orozco, G., Moore, D.J., Barton, A., Worthington, J., Wilson, A.G.  J Rheumatol. Rheumatoid Arthritis-associated Polymorphisms at 6q23 Are Associated with Radiological Damage in Autoantibody-positive RA.  2012 Sep;39(9):1781-5. (Abstract)
  4. Maxwell, J.R., Gowers, I.R., Kuet, K.P., Barton, A., Worthington, J., Wilson A.G.  Expression of the autoimmunity associated TNFAIP3 is increased in rheumatoid arthritis but does not differ according to genotype at 6q23. AG.Rheumatology (Oxford). 2012 Aug;51(8):1514-5. (Full text)
  5. Knevel, R., de Rooy, D.P., Gregersen, P.K., Lindqvist, E., Wilson, A.G., Gröndal, G., Zhernakova, A., van Nies, J.A., Toes, R.E., Tsonaka, R., Houwing-Duistermaat, J.J., Steinsson, K., Huizinga, T.W., Saxne T, van der Helm-van Mil AH.  Studying associations between variants in TRAF1-C5 and TNFAIP3-OLIG3 and the progression of joint destruction in rheumatoid arthritis in multiple cohorts. Ann Rheum Dis. 2012 Oct;71(10):1753-5. (Full text)
  6. MacKie, S.L., Taylor, J.C., Martin, S.G., Wordsworth, P., Steer, S., Wilson, A.G., Morgan, A.W. 2012. A spectrum of susceptibility to rheumatoid arthritis within HLA-DRB1: Stratification by autoantibody status in a large UK population. Genes Immun, 13(2), 120-128.  (Abstract)
  7. Robinson, J.I., Carr, I.M., Cooper, D.L., Rashid, L.H., Martin, S.G., Emery, P., Morgan, A.W.  2012. Confirmation of association of FCGR3B but not FCGR3A copy number with susceptibility to autoantibody positive rheumatoid arthritis. Human Mutation, 33(4), 741-749.  (Abstract)
  8. Knevel, R., Krabben, A., Brouwer, E., Posthumus, M.D., Wilson, A.G., Lindqvist, E., van der Helm-Van Mil, A. 2012. Genetic variants in IL15 associate with progression of joint destruction in rheumatoid arthritis: A multicohort study. Annals of the Rheumatic Diseases. (Abstract)
  9. Plant, D., Prajapati, R., Hyrich, K.L., Morgan, A.W., Wilson, A.G., Isaacs, J.D., Barton, A. 2012. Replication of association of the PTPRC gene with response to anti-tumor necrosis factor therapy in a large UK cohort. Arthritis and Rheumatism, 64(3), 665-670. (Abstract)
  10. Mackie, S.L., Taylor, J.C., Twigg, S., Martin, S.G., Steer, S., Worthington, J., Barton, A., Wilson, A.G., Hocking, L., Young, A., Emery, P., Barrett, J.H., Morgan, A.W.  2012.  Relationship between area-level socio-economic deprivation and autoantibody status in patients with rheumatoid arthritis: multicentre cross-sectional study. Ann Rheum Dis. (Abstract)
  11. Sarwar, N., A.S. Butterworth, et al. 2012. Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies. Lancet 379:1205-1213. (Abstract)

2011

  1. Gowers, I.R., K. Walters, E. Kiss-Toth, R.C. Read, G.W. Duff, and A.G. Wilson. 2011.  Age-related loss of CpG methylation in the tumour necrosis factor promoter.  Cytokine 56:792-797. (Abstract)
  2. Mackie, S.L., J.C. Taylor, S,G, Martin, P. Wordsworth, S. Steer, A.G. Wilson, J. Worthington, P. Emery, J.H. Barrett, and A.W. Morgan.  2011.  A spectrum of susceptibility to rheumatoid arthritis within HLA-DRB1:  stratification by autoantibody status in a large UK population.  Genes Immun.(Abstract)
  3. Plant, D., J. Bowes, C. Potter, K.L. Hyrich, A.W. Morgan, A.G. Wilson, J.D. Isaacs, and A. Barton. 2011. Genome-wide association study of genetic predictors of anti-tumor necrosis factor treatment efficacy in rheumatoid arthritis identifies associations with polymorphisms at seven loci. Arthritis Rheum 63:645-653. (Abstract)
  4. Orozco, G., S. Eyre, A. Hinks, J. Bowes, A.W. Morgan, A.G. Wilson, P. Wordsworth, S. Steer, L. Hocking, W. Thomson, J. Worthington, and A. Barton. 2011. Study of the common genetic background for rheumatoid arthritis and systemic lupus erythematosus. Ann Rheum Dis 70:463-468. (Abstract)
  5. Mewar, D., and A.G. Wilson. 2011. Treatment of rheumatoid arthritis with tumour necrosis factor inhibitors. Br J Pharmacol 162:785-791. (Abstract)
  6. Coulthard, L.R., J.C. Taylor, S. Eyre, J.I. Robinson, A.G. Wilson, J.D. Isaacs, K. Hyrich, P. Emery, A. Barton, J.H. Barrett, A.W. Morgan, and M.F. McDermott. 2011. Genetic variants within the MAP kinase signalling network and anti-TNF treatment response in rheumatoid arthritis patients. Ann Rheum Dis 70:98-103. (Abstract)

2010:

  1. Stahl, E.A., Raychaudhuri, S., Remmers, E.F., Xie, G., Eyre, S., Thomson, B.P., Li, Y., Kurreeman, F.A., Zhernakova, A., Hinks, A., et al. 2010. Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. Nat Genet 42:508-514. (Abstract)
  2. Craddock, N., Hurles, M.E., Cardin, N., Pearson, R.D., Plagnol, V., Robson, S., Vukcevic, D., Barnes, C., Conrad, D.F., Giannoulatou, E., et al. 2010. Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature 464:713-720. (Abstract)
  3. Cui, J., S. Saevarsdottir, B. Thomson, L. Padyukov, A.H. van der Helm-van Mil, J. Nititham, et al. 2010. PTPRC rheumatoid arthritis risk allele is also associated with response to anti-TNF therapy. Arthritis Rheum (Abstract)
  4. Marinou, I., K. Walters, J. Winfield, D.E. Bax, and A.G. Wilson. 2010. A gain of function polymorphism in the interleukin 6 receptor influences RA susceptibility. Ann Rheum Dis (Abstract)
  5. Orozco, G., S. Eyre, A. Hinks, X. Ke, A.G. Wilson, D.E. Bax, A.W. Morgan, P. Emery, S. Steer, L. Hocking, D.M. Reid, P. Wordsworth, P. Harrison, W. Thomson, A. Barton, and J. Worthington. 2009. Association of CD40 with rheumatoid arthritis confirmed in a large UK case-control study. Ann Rheum Dis (Abstract)
  6. Orozco, G., S. Eyre, A. Hinks, X. Ke, A.G. Wilson, D.E. Bax, A.W. Morgan, P. Emery, S. Steer, L. Hocking, D.M. Reid, P. Wordsworth, P. Harrison, W. Thomson, A. Barton, and J. Worthington. 2009. Association of CD40 with rheumatoid arthritis confirmed in a large UK case-control study. Ann Rheum Dis (Abstract)
  7. Robinson, J.I., J.H. Barrett, J.C. Taylor, M. Naven, D. Corscadden, A. Barton, A.G. Wilson, P. Emery, J.D. Isaacs, and A.W. Morgan. 2010. Dissection of the FCGR3A association with RA: increased association in men and with autoantibody positive disease. Ann Rheum Dis (Abstract)
  8. Potter, C., L.J. Gibbons, J.D. Bowes, H.J. Cordell, K. Hyrich, J.D. Isaacs, A.W. Morgan, A.G. Wilson, and A. Barton. 2010. Polymorphisms spanning the TNFR2 and TACE genes do not contribute towards variable anti-TNF treatment response. Pharmacogenet Genomics (Abstract)
  9. Marinou, I., J.R. Maxwell, and A.G. Wilson. 2010. Genetic influences modulating the radiological severity of rheumatoid arthritis. Ann Rheum Dis 69:476-482. (Abstract)
  10. Hassan, B., J.R. Maxwell, K.L. Hyrich, A. Barton, J. Worthington, J.D. Isaacs, A.W. Morgan, and A.G. Wilson. 2010. Genotype at the sIL-6R A358C polymorphism does not influence response to anti-TNF therapy in patients with rheumatoid arthritis. Rheumatology (Oxford) 49:43-47. (Abstract)
  11. Burr, M.L., H. Naseem, A. Hinks, S. Eyre, L.J. Gibbons, J. Bowes, A.G. Wilson, J. Maxwell, A.W. Morgan, P. Emery, S. Steer, L. Hocking, D.M. Reid, P. Wordsworth, P. Harrison, W. Thomson, J. Worthington, and A. Barton. 2010. PADI4 genotype is not associated with rheumatoid arthritis in a large UK Caucasian population. Ann Rheum Dis 69:666-670. (Abstract)

2009:

  1. Raychaudhuri, S., B.P. Thomson, E.F. Remmers, S. Eyre, A. Hinks, C. Guiducci, et al. 2009. Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk. Nat Genet 41:1313-1318. (Abstract)
  2. McClure, A., M. Lunt, S. Eyre, X. Ke, W. Thomson, A. Hinks, J. Bowes, L. Gibbons, D. Plant, A.G. Wilson, I. Marinou, A.W. Morgan, P. Emery, S. Steer, L.J. Hocking, D.M. Reid, P. Wordsworth, P. Harrison, J. Worthington, and A. Barton. 2009. Investigating the viability of genetic screening/testing for RA susceptibility using combinations of five confirmed risk loci. Rheumatology (Oxford) 48:1369-1374. (Abstract)
  3. Morgan, A.W., W. Thomson, S.G. Martin, A.M. Carter, H.A. Erlich, A. Barton, L. Hocking, D.M. Reid, P. Harrison, P. Wordsworth, S. Steer, J. Worthington, P. Emery, A.G. Wilson, and J.H. Barrett. 2009. Reevaluation of the interaction between HLA-DRB1 shared epitope alleles, PTPN22, and smoking in determining susceptibility to autoantibody-positive and autoantibody-negative rheumatoid arthritis in a large UK Caucasian population. Arthritis Rheum 60:2565-2576. (Abstract)
  4. Orozco, G., A. Hinks, S. Eyre, X. Ke, L.J. Gibbons, J. Bowes, E. Flynn, P. Martin, A.G. Wilson, D.E. Bax, A.W. Morgan, P. Emery, S. Steer, L. Hocking, D.M. Reid, P. Wordsworth, P. Harrison, W. Thomson, A. Barton, and J. Worthington. 2009. Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23. Hum Mol Genet 18:2693-2699. (Abstract)
  5. Maxwell, J.R., I.R. Gowers, and A.G. Wilson. 2009. Complex genetic association of 6q23 with autoimmune rheumatic conditions. Arthritis Res Ther 11:107. (Abstract)
  6. Barton, A., S. Eyre, X. Ke, A. Hinks, J. Bowes, E. Flynn, P. Martin, A.G. Wilson, A.W. Morgan, P. Emery, S. Steer, L.J. Hocking, D.M. Reid, P. Harrison, P. Wordsworth, W. Thomson, and J. Worthington. 2009. Identification of AF4/FMR2 family, member 3 (AFF3) as a novel rheumatoid arthritis susceptibility locus and confirmation of two further pan-autoimmune susceptibility genes. Hum Mol Genet. (Abstract)
  7. Bowes, J.D., C. Potter, L.J. Gibbons, K. Hyrich, D. Plant, A.W. Morgan, A.G. Wilson, J.D. Isaacs, J. Worthington, and A. Barton. 2009. Investigation of genetic variants within candidate genes of the TNFRSF1B signalling pathway on the response to anti-TNF agents in a UK cohort of rheumatoid arthritis patients. Pharmacogenet Genomics. (Abstract)
  8. Marinou, I., K. Walters, M.C. Dickson, M.H. Binks, D.E. Bax, and A.G. Wilson. 2009. Evidence of epistasis between Interleukin-1 and Selenoprotein-S with susceptibility to RA. Ann Rheum Dis. (Abstract)
  9. Read, R.C., D.M. Teare, A.C. Pridmore, S.C. Naylor, J.M. Timms, E.B. Kaczmarski, R. Borrow, and A.G. Wilson. 2009. The tumor necrosis factor polymorphism TNF (-308) is associated with susceptibility to meningococcal sepsis, but not with lethality. Crit Care Med.  (Abstract)
  10. Vignal, C., A.T. Bansal, D.J. Balding, M.H. Binks, M.C. Dickson, D.S. Montgomery, and A.G. Wilson. 2009. Genetic association of the major histocompatibility complex with rheumatoid arthritis implicates two non-DRB1 loci. Arthritis Rheum 60:53-62. (Abstract)
  11. Potter, C., K.L. Hyrich, A. Tracey, M. Lunt, D. Plant, D.P. Symmons, W. Thomson, J. Worthington, P. Emery, A.W. Morgan, A.G. Wilson, J. Isaacs, and A. Barton. 2009. Association of rheumatoid factor and anti-cyclic citrullinated peptide positivity, but not carriage of shared epitope or PTPN22 susceptibility variants, with anti-tumour necrosis factor response in rheumatoid arthritis. Ann Rheum Dis 68:69-74. (Abstract)

2008:

  1. Barton, A., W. Thomson, X. Ke, S. Eyre, A. Hinks, J. Bowes, D. Plant, L.J. Gibbons, A.G. Wilson, D.E. Bax, A.W. Morgan, P. Emery, S. Steer, L. Hocking, D.M. Reid, P. Wordsworth, P. Harrison, and J. Worthington. 2008. Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13. Nat Genet 40:1156-1159. (Abstract).
  2. Maxwell, J.R., C. Potter, K.L. Hyrich, Braggss, A. Barton, J. Worthington, J.D. Isaacs, A.W. Morgan, and A.G. Wilson. 2008. Association of the tumour necosis factor -308 variant with differential response to anti-TNF agents in the treatment of rheumatoid arthritis. Hum. Mol. Genet. (Abstract).
  3. Nile, C.J., R.C. Read, M. Akil, G.W. Duff, and A.G. Wilson. 2008. Methylation status of a single CpG site in the IL-6 promoter is related to IL-6 mRNA levels and rheumatoid arthritis. Arthritis Rheum (Abstract).
  4. Rioja, I., F.J. Hughes, C.H. Sharp, L.C. Warnock, D.S. Montgomery, M. Akil, A.G. Wilson, M.H. Binks, M.C. Dickson. 2008. CXCL13, CCL23, TGFα, TNFRSF9 and M-CSF are potential novel biomarkers of disease activity in Rheumatoid Arthritis patients. Arthritis Rheum 58:2257-2267. (Abstract)
  5. Marinou, I., S.H. Till, D.J. Moore, and A.G. Wilson. 2008. No evidence of association or interactions between the IL-4, IL-4R alpha and IL-13 genes and rheumatoid arthritis. Arthritis Res Ther 10:R80. (Abstract)
  6. Barton, A., W. Thomson, X. Ke, S. Eyre, A. Hinks, J. Bowes, L. Gibbons, D. Plant, A.G. Wilson, I. Marinou, A. Morgan, P. Emery, S. Steer, L. Hocking, D.M. Reid, P. Wordsworth, P. Harrison, and J. Worthington. 2008. Re-evaluation of putative rheumatoid arthritis susceptibility genes in the post-genome wide association study era and hypothesis of a key pathway underlying susceptibility. Hum Mol Genet (Abstract)
  7. Atif, U., A. Philip, J. Aponte, E.M. Woldu, S. Brady, V.B. Kraus, J.M. Jordan, M. Doherty, A.G. Wilson, R.W. Moskowitz, M. Hochberg, R. Loeser, J.B. Renner, and M. Chiano. 2008. Absence of association of asporin polymorphisms and osteoarthritis susceptibility in US Caucasians. Osteoarthritis Cartilage Abstract)
  8. Sheedy, F.J., I. Marinou, L.A. O'Neill, and A.G.Wilson. 2008. The Mal/TIRAP S180L and TLR4 G299D polymorphisms are not associated with susceptibility to or severity of rheumatoid arthritis. Ann Rheum Dis (Abstract)
  9. Cantaert, T., M.A. Stone, M. Terborg, R. Mog, N. de Vries, A.G. Wilson, P.P. Tak, and D. Baeten. 2008. A functional polymorphism of TIR-domain-containing adaptor protein is not associated with axial spondyloarthritis. Ann Rheum Dis (Abstract)
  10. Mewar, D., I. Marinou, A.L. Coote, D.J. Moore, M. Akil, D. Smillie, M.C. Dickson, M.H. Binks, D.S. Montgomery, and A.G. Wilson. 2008. Association between radiographic severity of rheumatoid arthritis and shared epitope alleles: differing mechanisms of susceptibility and protection. Ann Rheum Dis (Abstract)

2007:

  1. Thomson, W., A. Barton, X. Ke, S. Eyre, A. Hinks, J. Bowes, R. Donn, D. Symmons, S. Hider, I.N. Bruce, A.G. Wilson, I. Marinou, A. Morgan, P. Emery, A. Carter, S. Steer, L. Hocking, D.M. Reid, P. Wordsworth, P. Harrison, D. Strachan, and J. Worthington. 2007. Rheumatoid arthritis association at 6q23. Nat Genet 39:1431-3. (Abstract)
  2. Greetham, D., Ellis, C.D., Mewar, D., Fearon, U., Nic An Ultaigh, S., Veale, D.J., Guesdon, F., and Wilson, A.G. 2007. Functional characterisation of NF-kB inhibitor-like protein 1 (NFkBIL1), a candidate susceptibility gene for rheumatoid arthritis. Hum Mol Genet 16:3027-36. (Abstract)
  3. Gordon, A., L. Southam, J. Loughlin, A.G. Wilson, I. Stockley, A.J. Hamer, R. Eastell, and J.M. Wilkinson. 2007. Variation in the Secreted Frizzled-Related Protein-3 Gene and Risk of Osteolysis and Heterotopic Ossification After Total Hip Arthroplasty. J Orthopaedic Res 25:1665-70. (Abstract)
  4. Wilson, A., and G. Duff. 2007. Translating immunobiology into clinical therapeutics. Curr Opin Pharmacol 7:410-411. (Abstract)
  5. Marinou, I., J. Healy, D. Mewar, D.J. Moore, M.C. Dickson, M.H. Binks, D.S. Montgomery, K. Walters, and A.G. Wilson. 2007. Association of interleukin-6 and interleukin-10 genotypes with radiographic damage in rheumatoid arthritis is dependent on autoantibody status. Arthritis Rheum 56:2549-2556. (Abstract)
  6. Sung, H.Y., H. Guan, A. Czibula, A.R. King, K. Eder, E. Heath, S.K. Suvarna, S.K. Dower, A.G. Wilson, S.E. Francis, D.C. Crossman, and E. Kiss-Toth. 2007. Human tribbles-1 controls proliferation and chemotaxis of smooth muscle cells via MAPK signaling pathways. J Biol Chem 282:18379-18387. (Abstract)
  7. Marinou, I., D.S. Montgomery, M.C. Dickson, M.H. Binks, D.J. Moore, D.E. Bax, and A.G. Wilson. 2007. The Interferon-induced helicase domain 1 A946G polymorphism is not associated with rheumatoid arthritis. Arthritis Res Ther 9:R40. (Abstract)
  8. Kraus, V.B., J.M. Jordan, M. Doherty, A.G. Wilson, R. Moskowitz, M. Hochberg, R. Loeser, M. Hooper, J.B. Renner, M.M. Crane, P. Hastie, S. Sundseth, and U. Atif. 2007. The Genetics of Generalized Osteoarthritis (GOGO) study: study design and evaluation of osteoarthritis phenotypes. Osteoarthritis Cartilage 15:120-127. (Abstract)