Dr Amaka Offiah BSc, MBBS, MRCP, FRCR, PhD, FRCPCHAmaka Offiah

Reader in Paediatric Musculoskeletal Imaging

Department of Oncology & Metabolism
Academic Unit of Child Health
Sheffield Children's NHS Foundation Trust
Western Bank
Sheffield
S10 2TH

Office: Room C4, Stephenson Wing

Telephone: +44 (0)114 2717557  
Fax: +44 (0)114 2755364
Email: a.offiah@sheffield.ac.uk

Secretary: Gillian Griffiths
Telephone: +44 (0)114 215 9048
Email: g.l.griffiths@sheffield.ac.uk

Biography

My undergraduate training took place in Nigeria.

I obtained my MBBS while working at Oldchurch Hospital, Essex and then trained as a radiologist in Sheffield. I moved back to London, to Great Ormond Street Hospital and the Institute of Child Health, where I obtained a PhD for my thesis, “Optimisation of the digital radiographic imaging of suspected non-accidental injury”.

I returned to Sheffield as a HEFCE-funded Clinical Senior Lecturer in the Academic Unit of Child Health and was promoted to Reader in Paediatric Musculoskeletal Imaging in January 2015.

Research Interests

I am interested in the imaging of suspected child abuse and skeletal dysplasias and in methods of determining which children have fragile bones prone to fracture and which do not. More specifically, I am concentrating on the optimisation of current techniques and development of novel methods of distinguishing brittle from normal bones, in understanding the mechanisms of accidental injury in children, in developing objective imaging biomarkers and normative data for the paediatric musculoskeletal system including post-mortem imaging and in diagnosing fractures in the Emergency Department.

Teaching Interests

I contribute to the teaching of Radiology Specialist Registrars on rotation at Sheffield Children’s Hospital. I offer SSC and BMedSci attachments to medical students and currently co-supervise 5 PhD students. I give a large number of invited local and national lectures on various radiology, paediatric, genetic, emergency medicine and orthopaedic courses. I am an instructor on the biannual Instructional Course organised by the Skeletal Dysplasia Group for Teaching and Research and helped to develop and then taught on the inaugural national skeletal dysplasia course held in Bangalore, India in August 2010. I have contributed chapters to several well-respected radiology textbooks, and am co-author of two books, “A Radiological Atlas of Child Abuse” and “Fetal and Perinatal Skeletal Dysplasias: An Atlas of Multimodality Imaging”.  I am a Fellow of the Higher Education Academy.

Professional Activities                                               

I chair both the Child Abuse Taskforce of the European Society of Paediatric Radiologists and the Skeletal Dysplasia Group for Teaching and Research and am Vice-Chair of the Sheffield Research Ethics Committee. I am a Panel Member of the European Skeletal Dysplasia Network (ESDN) and a committee member of the International Consortium for Vertebral Anomalies & Scoliosis. I am a Partner Governor on the Board of Sheffield Children's NHS Foundation Trust, representing the University of Sheffield, and sit on various other committees including the Sheffield Children's Hospital Scientific Advisory Committee and Sheffield Children's Hospital Research Committee.   I act as an expert witness for the courts in cases of suspected child abuse.  

Current Projects

  • Biomechanics of fractures in children
  • COMBAT: COMputerised Bone Age Tool
  • Post-mortem computerized tomography in children
  • Vertebral fracture diagnosis in children
  • HRpQCT in osteogenesis imperfecta
  • Bone response to exercise and vitamin D
  • Assessment of visual expertise
  • Relationship between vitamin D levels, radiographic rickets and fractures
  • Imaging in suspected child physical abuse
  • Development of a dynamic Radiological Electronic Atlas of Malformation Syndromes (dREAMS)                                                                                                                                                                                                                                                                                                                                                                   

Key Publications

Li X, Viceconti M, Cohen MC, Reilly G, Carre MJ, Offiah AC Developing CT based computational models of pediatric femurs J Biomech July 2015 http://dx.doi.org/10.1016/j.jbiomech.2015.03.027

Thayyil S, Sebire NH, Chitty LS, Wade A, Chong W, Olsen O, Gunny RS, Offiah AC, Owens CM, Saunders DE, Scott RJ, Jones R, Norman W, Addison S, Bainbridge A, Cady EB, Vita ED, Robertson NJ, Taylor AM;  for the MARIAS collaborative group.  Post-mortem MRI versus conventional autopsy in foetuses and children:  a prospective validation study.  Lancet May 2013, 2013 (E pub ahead of print)

Bochukova E, Schoenmakers N, Agostini M, Schoenmakers E, Rajanayagam O, Keogh JM, Henning E, Reinemund J, Gevers E, Sarri M, Downes K, Offiah A et al Growth retardation and severe constipation due to a dominant negative mutation in the thyroid hormone receptor alpha gene. New Engl J Med 2012;366:243-249

Leung R, Nwachukwu C, Pervaiz A, Landes C, Offiah AC Are UK radiologists satisfied with training and support received in suspected child physical abuse? Clin Radiol 2009;64:690 – 698

Thayyil S, Cleary JO, Sebire NJ, Scott R, Chong WK “Klling”, Gunny R, Owens C, Olsen O, Offiah A, Parkes HG, Chitty L, Price AN, Yousry T, Robertson NJ, Lythgoe MF, Taylor AM Post mortem examination of human fetuses: a comparison of whole-body high-field MRI at 9.4T with conventional MRI and invasive autopsy Lancet 2009;374:467 – 475