Standard Operating Procedures

Since opening in September 2006 the NIHR Sheffield CRF has developed fully documented systems and procedures as part of its Quality Control Strategy. All procedures comply with Trust and University policies including Clinical and Research Governance, Health and Safety, Infection Control and Fire.

The safety of the staff and research participants is of paramount importance.

A comprehensive directory of Standard Operating Procedures is available for use by all staff and users of the CRF. Standard Operating Procedures are available for Clinical, Laboratory, Administration and Project Management Procedures.

• Clinical Procedures
• Laboratory Procedures
• Administration Procedures
• Project Management Procedures

A range of information booklets and packs has been produced to provide essential information to research participants, researchers and sponsors wishing to use the NIHR Sheffield CRF. To obtain any of these documents or SOPs please contact Karen French, NIHR Sheffield CRF Manager.

Clinical Procedures

CRF.C102	Measuring Pulse (PDF)
CRF.C103	Measuring Blood Pressure (PDF)
CRF.C104	Measuring Respiratory Rate (PDF)
CRF.C106	Measuring Height (PDF)
CRF.C107	Measuring Blood Pressure using the Dash 5000 patient monitor (PDF)
CRF.C108	Measuring Body Mass Index (PDF)
CRF.C109	Measuring Peak Flow (PDF)
CRF.C110	Measuring Oxygen Saturation using the Dinamap monitor (PDF)
CRF.C111	Venepuncture using Needle and Syringe (PDF)
CRF.C112	Venepuncture using Vacutainer and Syringe Butterfly (PDF)
CRF.C113	Measuring Tympanic Temperature (PDF)
CRF.C114	Measuring Weight using electronic scales (PDF)
CRF.C115	Insertion and Management of a Peripheral Venous Cannula (PDF)
CRF.C116	Blood Glucose Monitoring (PDF)
CRF.C117	Standard 12 lead ECG Recording - Using the MAC 1200 (PDF)
CRF.C119	Measuring Oxygen Saturation Measurement using the Dash 5000 patient monitor (PDF)
CRF.C120	Oxygen Cylinder Checks (PDF)
CRF.C121	Visual Acuity Testing (PDF)
CRF.C123	Venepuncture using Vacutainer (PDF)
CRF.C124	Conducting Routine Clinical Checks in the CRF (PDF)
CRF.C125	Obtaining a blood sample from a Peripheral Venous Cannula (PDF)
CRF.C126	Removal of a Peripheral Venous Cannula (PDF)
CRF.C127	Admitting patients to the Dash 5000 Patient Monitor (PDF)
CRF.C128	Discharging patients from the Dash 5000 Patient Monitor (PDF)
CRF.C129	Measuring Weight using non-electronic scales (PDF)
CRF.C130	Grip Strength Testing (PDF)
CRF.C131	Measuring the Circumference of the Hips (PDF)
CRF.C132	Measuring the Circumference of the Waist (PDF)
CRF.C133	Measuring Waist to Hip Ratio (PDF)
CRF.C134	Urine Pregnancy Test (PDF)
CRF.C135	Measuring Height Electronically Using the SECA Height Measurement Unit (PDF)
CRF.C136	Measuring Weight Electronically Using the SECA Weight Measurement Unit (PDF)
CRF.C137	Standard 12 lead ECG Recording - Using the MAC 5500 (PDF)
CRF.C138	Engaging Medical Staff in Infection Prevention and Control (PDF)

Laboratory Procedures

CRF.L101	Processing and Aliquoting Blood Specimens (PDF)
CRF.L102	Performing blood smears (PDF)
CRF.L103	Use of the Centrifuge (PDF)
CRF.L104	Storage of Samples -80ºC freezer (PDF)
CRF.L105	Procedure for dealing with spillages (PDF)
CRF.L106	Storage of samples -20ºC freezer
CRF.L108	Cleaning and disinfection of the sample processing areas (PDF)
CRF.L109	Use of the refrigerated Centrifuge (PDF)
CRF.L110	Clinical Waste Management (PDF)
CRF.L111	Safe Handling of Dry Ice (PDF)

Administration Procedures

CRF.A100	Writing, Management of and Training in Standard Operating Procedures in the Sheffield Clinical Research Facility (PDF)
CRF.A101	Electronic Filing of Documentation within the CRF Projects Folder (PDF)
CRF.A102	Approach and Identification of Participants for Research Studies - Inpatient Areas (PDF)
CRF.A103	Approach and Identification of Participants for Research Studies - Outpatient Areas (PDF)
CRF.A104	Approach and Identification of Participants for Research Studies - Previously Attended STH Hospital (PDF)
CRF.A105	Equipment Management (PDF)

Project Management Procedures

CRF.PM119

Regulatory Inspection (PDF)