The University of Sheffield
National Institute for Health Research Sheffield Clinical Research Facility

Publications

Investigators are continually providing the NIHR Sheffield CRF with publication information regarding the clinical research studies that required CRF facilities and support. The type of publication information collected includes papers, chapters, abstracts and presentations. Since opening in 2006, 67 papers and 3 abstracts have been published and in addition 14 presentations at national and international meetings have been given, promoting clinical research at the NIHR Sheffield CRF.

Publications from 2012

to be confirmed.

 

Publications from 2011

1. Andrews R, Shah K, Wilkinson M, Gartland A. (2011): Effects of cobalt and chromium ions at clinically equivalent concentrations after metal-on-metal hip replacement on human osteoblasts and osteoclasts: Implications for skeletal health. Bone, e-pub, accepted 05.06.11.

2. Beard J, Marriott J, Purdie H and Crossley J. (2011): Assessing the surgical skills of trainees in the operating theatre: a prospective observational study of the methodology. Health Technol Assess, 15(1):1-162.

3. Bidlingmaier M, Kim J, Savoy C, Kim M, Ebrecht N, de la Motte S and Strasburger C. (2011): Comparative Pharmacokinetics and Pharmacodynamics of a New Sustained-Release Growth Hormone (GH), LB03002, Versus Daily GH in Adults with GH Deficiency. J Clin Endo Metabolism, 91(8):2926–30.

4. Coulthard L, Taylor J, Eyre S, Robinson J, Wilson A, Isaacs J, Hyrich K, Emery P, Barton A, Barrett J, Morgan A and McDermott M. (2011): Genetic variants within the MAP kinase signalling network and anti-TNF treatment response in rheumatoid arthritis patients. Ann Rheum Dis, 70:98-103.

5. Crossley J, Marriott J, Purdie H and Beard J. (2011): Prospective observational study to evaluate NOTSS (Non-Technical Skills for Surgeons) for assessing trainees’ non-technical performance in the operating theatre. Br J Surgery, 98(7):1010-20.

6. Darton T, Wing J, Lees A, Heath A, Read R. (2011): Adult survivors of invasive pneumococcal disease exhibit defective B cell function. Clin Infect Dis, 52(9):1133-6.

7. Evans C, Pratt C, Matheson M, Vaughan T, Findlow J, Borrow R, Gorringe A, Read R. (2011): Nasopharyngeal colonization by Neisseria lactamica and induction of protective immunity against Neisseria meningitidis. Clin Infect Dis, 52(1):70-7.

8. Findlow H, Borrow R, Hardelid P, Newton E, Frankland S, Naylor S, Miller E, Kaczmarski E, Read R. (2011): Serum antibody kinetics following nasal or parenteral challenge with meningococcal polysaccharide in healthy adults. Clin Vaccine Immunol, 18(3):424-9.

9. Nicholson K, Abrams K, Batham S, Clark T, Hoschler K, Lim W, Medina M, Nguyen-Van-Tam J, Read R, Warren F, Zambon M. (2011): Immunogenicity and safety of a two-dose schedule of whole-virion and AS03A-adjuvanted 2009 influenza A (H1N1) vaccines: a randomised, multicentre, age-stratified, head-to-head trial. Lancet Infect Dis, 11(2):91-101.

10. Orozco G, Eyre S, Hinks A, Bowes J, Morgan A, Wilson A, Wordsworth P, Steer S, Hocking L, Thomson W, Worthington J and Barton A. (2011): Study of the common genetic background for rheumatoid arthritis and systemic lupus erythematosus. Ann Rheum Dis, 70:463-8.

11. Plant D, Bowes J, Potter C, Hyrich K, Morgan A, Wilson A, Isaacs J and Barton A. (2011): Genome-wide association study of genetic predictors of anti-tumor necrosis factor treatment efficacy in rheumatoid arthritis identifies associations with polymorphisms at seven loci. Arthritis Rheum, 63:645-53.

12. Powers H, Hill M, Mushtaq S, Dainty J, Majsak-Newman G, Williams E. (2011): Correcting a marginal riboflavin deficiency improves hematologic status in young women in the United Kingdom (RIBOFEM). Am J Clin Nutrition, 93(6):1274-84.

13. Wing J, Smart L, Borrow R, Findlow J, Findlow H, Heath A, Read R. (2011): Kinetics of immune responses to nasal challenge with meningococcal polysaccharide one year after serogroup-C glycoconjugate vaccination. Clin Infect Dis, 52(11):1317-23.

Publications from 2010

1. Burr M, Naseem H, Hinks A, Eyre S, Gibbons L, Bowes J, Wilson A, Maxwell J, Morgan A, Emery P, Steer S, Hocking L, Reid D, Wordsworth P, Harrison P, Thomson W, Worthington J and Barton A. (2010): PADI4 genotype is not associated with rheumatoid arthritis in a large UK Caucasian population. Ann Rheum Dis, 69:666-70.

2. Craddock N, Hurles M, Cardin N, Pearson R, Plagnol V, Robson S, Vukcevic D, Barnes C, Conrad D, Giannoulatou E, Holmes C, Marchini J, Stirrups K, Tobin M, Wain L, Yau C, Aerts J, Ahmad T, Andrews T, Arbury H, Attwood, Auton A, Ball S, Balmforth A, Barrett J, Barroso I, Barton A, Bennett A, Bhaskar S, Blaszczyk K, Bowes J, Brand O, Braund P, Bredin F, Breen G, Brown M, Bruce I, Bull J, Burren O, Burton J, Byrnes J, Caesar S, Clee C, Coffey A, Connell J, Cooper J, Dominiczak A, Downes K, Drummond H, Dudakia D, Dunham A, Ebbs B, Eccles D, Edkins S, Edwards C, Elliot A, Emery P, Evans D, Evans G, Eyre S, Farmer A, Ferrier I, Feuk L, Fitzgerald T, Flynn E, Forbes A, Forty L, Franklyn J, Freathy R, Gibbs P, Gilbert P, Gokumen O, Gordon-Smith K, Gray E, Green E, Groves C, Grozeva D, Gwilliam R, Hall A, Hammond N, Hardy M, Harrison P, Hassanali N, Hebaishi H, Hines S, Hinks A, Hitman G, Hocking L, Howard E, Howard P, Howson J, Hughes J, Hunt S, Isaacs J, Jain M, Jewell D, Johnson T, Jolley J, Jones I, Jones L, Kirov G, Langford C, Lango-Allen H, Lathrop G, Lee J, Lee K, Lees C, Lewis K, Lindgren C, Maisuria-Armer M, Maller J, Mansfield J, Martin P, Massey D, McArdle W, McGuffin P, McLay K, Mentzer A, Mimmack M, Morgan A, Morris A, Mowat C, Myers S, Newman W, Nimmo E, O'Donovan M, Onipinla A, Onyiah I, Ovington N, Owen M, Palin K, Parnell K, Pernet D, Perry J, Phillips A, Pinto D, Prescott N, Prokopenko I, Quail M, Rafelt S, Rayner N, Redon R, Reid D, Renwick, Ring S, Robertson N, Russell E, St Clair D, Sambrook J, Sanderson J, Schuilenburg H, Scott C, Scott R, Seal S, Shaw-Hawkins S, Shields B, Simmonds M, Smyth D, Somaskantharajah E, Spanova K, Steer S, Stephens J, Stevens H, Stone M, Su Z, Symmons D, Thompson J, Thomson W, Travers M, Turnbull C, Valsesia A, Walker M, Walker N, Wallace C, Warren-Perry M, Watkins N, Webster J, Weedon M, Wilson A, Woodburn M, Wordsworth B, Young A, Zeggini E, Carter N, Frayling T, Lee C, McVean G, Munroe P, Palotie A, Sawcer S, Scherer S, Strachan D, Tyler-Smith C, Brown M, Burton P, Caulfield M, Compston A, Farrall M, Gough S, Hall A, Hattersley A, Hill A, Mathew C, Pembrey M, Satsangi J, Stratton M, Worthington J, Deloukas P, Duncanson A, Kwiatkowski D, McCarthy M, Ouwehand W, Parkes M, Rahman N, Todd J, Samani N and Donnelly P. (2010): Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature, 464:713-20.

3. Cui J, Saevarsdottir S, Thomson B, Padyukov L, van der Helm-van Mil A, Nititham J, Hughes L, de Vries N, Raychaudhuri S, Alfredsson L, Askling J, Wedren S, Ding B, Guiducci C, Wolbink G, Crusius J, van der Horst-Bruinsma I, Herenius M, Weinblatt M, Shadick N, Worthington J, Batliwalla F, Kern M, Morgan A, Wilson A, Isaacs J, Hyrich K, Seldin M, Moreland L, Behrens T, Allaart C, Criswell L, Huizinga T, Tak P, Bridges S, Toes Jr R, Barton A, Klareskog L, Gregersen P, Karlson E and Plenge R. (2010): Rheumatoid arthritis risk allele PTPRC is also associated with response to anti-tumor necrosis factor alpha therapy. Arthritis Rheum, 62:1849-61.

4. Eyre S, Flynn E, Martin P, Hinks A, Wilson A, Morgan A, Emery P, Steer S, Hocking L, Reid D, Harrison P, Wordsworth P, Thomson W, Worthington J and Barton A. (2010): No evidence for association of the KLF12 gene with rheumatoid arthritis in a large UK cohort. Ann Rheum Dis, 69:1407-8.

5. Eyre S, Hinks A, Bowes J, Flynn E, Martin P, Wilson A, Morgan A, Emery P, Steer S, Hocking L, Reid D, Harrison P, Wordsworth P, Thomson W, Worthington J, and Barton A. (2010): Overlapping genetic susceptibility variants between three autoimmune disorders: rheumatoid arthritis, type 1 diabetes and coeliac disease. Arthritis Res Ther,12:R175.

6. Eyre S, Hinks A, Flynn E, Martin P, Wilson A, Maxwell J, Morgan A, Emery P, Steer S, Hocking L, Reid D, Harrison P, Wordsworth P, Thomson W, Worthington J and Barton A. (2010): Confirmation of association of the REL locus with rheumatoid arthritis susceptibility in the UK population. Ann Rheum Dis, 69:1572-3.

7. Foster R, Carlring J, Lees A, Borrow R, Ramsay M, Kacsmarski E, Miller E, McKendrick M, Heath A, Read R. (2010): Functional T-cell deficiency in adolescents who experience serogroup C meningococcal disease despite receiving the meningococcal serogroup C conjugate vaccine. Clin Vaccine Immunol, 17(7):1104-10.

8. Hassan B, Maxwell J, Hyrich K, Barton A, Worthington J, Isaacs J, Morgan A and Wilson A. (2010): Genotype at the sIL-6R A358C polymorphism does not influence response to anti-TNF therapy in patients with rheumatoid arthritis. Rheumatology (Oxford), 49:43-7.

9. Hind D, O'Cathain A, Cooper C, Parry G, Isaac C, Rose A, Martin L and Sharrack B. (2010):The acceptability of computerised cognitive behavioural therapy for the treatment of depression in people with chronic physical disease: A qualitative study of people with multiple sclerosis. Psychology & Health, 25(6):699-712.

10. Judge H, Patil S, Buckland R, Jakubowski J and Storey R. (2010): Potentiation of clopidogrel active metabolite formation by rifampicin leads to greater P2Y12 receptor blockade and inhibition of platelet aggregation after clopidogrel. J Thrombosis and Haemostasis, 8:1820–7.

11. Marinou I, Maxwell J and Wilson A. (2010): Genetic influences modulating the radiological severity of rheumatoid arthritis. Ann Rheum Dis, 69:476-82.

12. Marriott J, Purdie H, Crossley J and Beard J. (2010): Evaluation of procedure-based assessment for assessing trainees’ skills in the operating theatre. Br J Surgery, 98(3):450-7.

13. Maxwell J, Gowers I, Moore D and Wilson A. (2010): Alcohol consumption is inversely associated with risk and severity of rheumatoid arthritis. Rheumatology (Oxford), 49:2140-6.

14. Nicholson K, Abrams K, Batham S, Clark T, Hoschler K, Lim W, Medina M, Nguyen-Van-Tam J, Read R, Warren F, Zambon M. (2010): A randomised, partially observer blind, multicentre, head-to-head comparison of a two-dose regimen of Baxter and GlaxoSmithKline H1N1 pandemic vaccines, administered 21 days apart. Health Technol Assess, 14(55):193-334.

15. Orozco G, Eyre S, Hinks A, Ke X, Wilson A, Bax D, Morgan A, Emery P, Steer S, Hocking L, Reid D, Wordsworth P, Harrison P, Thomson W, Barton A and Worthington J (2010): Association of CD40 with rheumatoid arthritis confirmed in a large UK case-control study. Ann Rheum Dis, 69:813-6.

16. Potter C, Cordell H, Barton A, Daly A, Hyrich K, Mann D, Morgan A, Wilson A and Isaacs J. (2010): Association between anti-tumour necrosis factor treatment response and genetic variants within the TLR and NF{kappa}B signalling pathways. Ann Rheum Dis, 69:1315-20.

17. Potter C, Gibbons L, Bowes J, Cordell H, Hyrich K, Isaacs J, Morgan A, Wilson A and Barton A. (2010): Polymorphisms spanning the TNFR2 and TACE genes do not contribute towards variable anti-TNF treatment response. Pharmacogenet Genomics, 20:338-41.

18. Rezaei N, Wing J, Aghamohammadi A, Carlring J, Lees A, Asgarian-Omran H, Pourpak Z, Sarrafnejad A, Kardar G, Shahrestani T, Masoumi F, Zare A, Saghafi S, Sarrafzadeh S, Foster R, Heath A, Read R. (2010): B-cell-T-cell activation and interaction in common variable immunodeficiency. Hum Immunol, 71(4):355-62.

19. Robinson J, Barrett J, Taylor J, Naven M, Corscadden D, Barton A, Wilson A, Emery P, Isaacs J and Morgan A. (2010): Dissection of the FCGR3A association with RA: increased association in men and with autoantibody positive disease. Ann Rheum Dis, 69:1054-7.

20. Stahl E, Raychaudhuri R, Remmers E, Xie G, Eyre S, Thomson B, Li Y, Kurreeman F, Zhernakova A, Hinks A, Guiducci C, Chen R, Alfredsson L, Amos C, Ardlie K, Barton K, Bowes J, Brouwer E, Burtt N, Catanese J, Coblyn J, Coenen M, Costenbader K, Criswell L, Crusius J, Cui J, de Bakker P, De Jager P, Ding B, Emery P, Flynn E, Harrison P, Hocking L, Huizinga T, Kastner D, Ke X, Lee A, Liu X, Martin P, Morgan A, Padyukov L, Posthumus M, Radstake T, Reid D, Seielstad M, Seldin M, Shadick N, Steer S, Tak P, Thomson W, van der Helm-van Mil A, van der Horst-Bruinsma I, van der Schoot C, van Riel, M.E. Weinblatt P, Wilson A, Wolbink G, Wordsworth B, Wijmenga C, Karlson E, Toes R, de Vries N, Begovich A, Worthington J, Siminovitch K, Gregersen P, Klareskog L and Plenge R. (2010): Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. Nat Genet, 42:508-14.

21. Tan R, Gibbons L, Potter C, Hyrich K, Morgan A, Wilson A, Isaacs J and Barton A. (2010): Investigation of rheumatoid arthritis susceptibility genes identifies association of AFF3 and CD226 variants with response to anti-tumour necrosis factor treatment. Ann Rheum Dis, 69:1029-35.

22. Wright A, King M, Wolfe C, Powers H, Finglas P. (2010): Comparison of (6 S)-5-methyltetrahydrofolic acid v. folic acid as the reference folate in longer-term human dietary intervention studies assessing the relative bioavailability of natural food folates: comparative changes in folate status following a 16-week placebo-controlled study in healthy adults. Br J Nutrition, 103(5):724-9.

Publications from 2008-2009

1. Barton A, Eyre S, Ke X, Hinks A, Bowes J, Flynn E, Martin P, Wilson A, Morgan A, Emery P, Steer S, Hocking L, Reid D, Harrison P, Wordsworth P, Thomson W and Worthington J. (2009): Identification of AF4/FMR2 family, member 3 (AFF3) as a novel rheumatoid arthritis susceptibility locus and confirmation of two further pan-autoimmune susceptibility genes. Hum Mol Genet,18:2518-22.

2. Barton A, Thomson W, Ke X, Eyre S, Hinks A, Bowes J, Gibbons L, Plant D, Wilson A, Marinou I, Morgan A, Emery P, Steer S, Hocking L, Reid D, Wordsworth P, Harrison P and Worthington J. (2008): Re-evaluation of putative rheumatoid arthritis susceptibility genes in the post-genome wide association study era and hypothesis of a key pathway underlying susceptibility. Hum Mol Genet, 17:2274-9.

3. Barton A, Thomson W, Ke X, Eyre S, Hinks A, Bowes J, Plant D, Gibbons L, Wilson A, Bax D, Morgan A, Emery P, Steer S, Hocking L, Reid D, Wordsworth P, Harrison P, and Worthington J. (2008): Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13. Nat Genet, 40:1156-9.

4. Beard J. (2008): Assessment of surgical skills of trainees in the UK Ann R Coll Surg Engl, 90(4):282-5.

5. Bowes J, Potter C, Gibbons L, Hyrich K, Plant D, Morgan A, Wilson A, Isaacs J, Worthington J and Barton A. (2009): Investigation of genetic variants within candidate genes of the TNFRSF1B signalling pathway on the response to anti-TNF agents in a UK cohort of rheumatoid arthritis patients. Pharmacogenet Genomics 19:319-23.

6. Foster R, Carlring J, McKendrick M, Lees A, Borrow R, Read R, Heath A (2009): Evidence of a functional B-cell immunodeficiency in adults who experience serogroup C meningococcal disease. Clin Vaccine Immunol, 16(5):692-8.

7. Gorringe A, Taylor S, Brookes C, Matheson M, Finney M, Kerr M, Hudson M, Findlow J, Borrow R, Andrews N, Kafatos G, Evans CM, Read R. (2009): Phase I safety and immunogenicity study of a candidate meningococcal disease vaccine based on Neisseria lactamica outer membrane vesicles. Clin Vaccine Immunol, 16(8):1113-20.

8. Marinou I, Till S, Moore D and Wilson A. (2008): No evidence of
association or interactions between the IL-4, IL-4R alpha and IL-13 genes and rheumatoid arthritis. Arthritis Res Ther, 10:R80.

9. Marinou I, Walters K, Dickson M, Binks M, Bax D and Wilson A. (2009): Evidence of epistasis between interleukin 1 and selenoprotein-S with susceptibility to rheumatoid arthritis. Ann Rheum Dis, 68:1494-7.

10. Maxwell J, Gowers I and Wilson A. (2009): Complex genetic association of 6q23 with autoimmune rheumatic conditions. Arthritis Res Ther, 11:107.

11. Maxwell J, Potter C, Hyrich K, Barton A, Worthington J, Isaacs J, Morgan A and Wilson A. (2008): Association of the tumour necrosis factor-308 variant with differential response to anti-TNF agents in the treatment of rheumatoid arthritis. Hum Mol Genet, 17:3532-8.

12. Mewar D, Marinou I, Coote A, Moore D, Akil M, Smillie D, Dickson M, Binks M, Montgomery D and Wilson A. (2008): Association between radiographic severity of rheumatoid arthritis and shared epitope alleles: differing mechanisms of susceptibility and protection. Ann Rheum Dis, 67:980-3.

13. Morgan A, Thomson W, Martin S, Carter A, Erlich H, Barton A, Hocking L, Reid D, Harrison P, Wordsworth P, Steer S, Worthington J, Emery P, Wilson A, and Barrett J. (2009): Reevaluation of the interaction between HLA-DRB1 shared epitope alleles, PTPN22, and smoking in determining susceptibility to autoantibody-positive and autoantibody-negative rheumatoid arthritis in a large UK Caucasian population. Arthritis Rheum, 60:2565-76.

14. Mushtaq S, Su H, Hill M, Powers H. (2009): Erythrocyte pyridoxamine phosphate oxidase activity: a potential biomarker of riboflavin status? Am J Clin Nutrition, 90(5):1151-9.

15. Nile C, Read R, Akil A, Duff G and Wilson A. (2008): Methylation status of a single CpG site in the IL6 promoter is related to IL6 messenger RNA levels and rheumatoid arthritis. Arthritis Rheum, 58:2686-93.

16. Orozco G, Hinks A, Eyre S, Ke X, Gibbons L, Bowes J, Flynn E, Martin P, Wilson A, Bax D, Morgan A, Emery P, Steer S, Hocking L, Reid D, Wordsworth P, Harrison P, Thomson W, Barton A and Worthington J. (2009): Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23. Hum Mol Genet, 18:2693-9.

17. Plant D, Barton A, Thomson W, Ke X, Eyre S, Hinks A, Bowes J, Gibbons L, Wilson A, Marinou I, Morgan A, Steer S, Hocking L, Reid D, Wordsworth P, Harrison P and Worthington J. (2009):. A re-evaluation of three putative functional single nucleotide polymorphisms in rheumatoid arthritis. Ann Rheum Dis, 68:1373-5.

18. Potter C, Hyrich K, Tracey A, Lunt M, Plant D, Symmons D, Thomson W, Worthington J, Emery P, Morgan A, Wilson A, Isaacs J and Barton A. (2009): Association of rheumatoid factor and anti-cyclic citrullinated peptide positivity, but not carriage of shared epitope or PTPN22 susceptibility variants, with anti-tumour necrosis factor response in rheumatoid arthritis. Ann Rheum Dis, 68:69-74.

19. Raychaudhuri S, Thomson B, Remmers E, Eyre S, Hinks A, Guiducci C, Catanese J, Xie G, Stahl E, Chen R, Alfredsson L, Amos C, Ardlie K, Barton A, Bowes J, Burtt N, Chang M, Coblyn J, Costenbader K, Criswell L, Crusius J, Cui J, De Jager P, Ding B, Emery P, Flynn E, Harrison P, Hocking L, Huizinga T, Kastner D, Ke X, Kurreeman F, Lee A, Liu X, Li Y, Martin P, Morgan A, Padyukov L, Reid D, Seielstad M, Seldin M, Shadick N, Steer S, Tak P, Thomson W, van der Helm-van Mil A, van der Horst-Bruinsma I, Weinblatt M, Wilson A, Wolbink G, Wordsworth P, Altshuler D, Karlson E, Toes R, de Vries N, Begovich A, Siminovitch K, Worthington J, Klareskog L, Gregersen P, Daly M and Plenge R. (2009): Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk. Nat Genet, 41:1313-8.

20. Rioja I, Hughes F, Sharp C, Warnock L, Montgomery D, Akil M, Wilson A, Binks M and Dickson M. (2008): Potential novel biomarkers of disease activity in rheumatoid arthritis patients: CXCL13, CCL23, transforming growth factor alpha, tumor necrosis factor receptor superfamily member 9, and macrophage colony-stimulating factor. Arthritis Rheum. 58:2257-67.

21. Sheedy F, Marinou I, O'Neill L and Wilson A. (2008): The Mal/TIRAP S180L and TLR4 G299D polymorphisms are not associated with susceptibility to, or severity of, rheumatoid arthritis. Ann Rheum Dis, 67:1328-31.

22. Soreny C. (2009): Neuroscience nurses’ perceptions of caring for challenging patients. Br J Neuroscience Nursing, 5(9):425-31.

23. Vignal C, Bansal A, Balding D, Binks M, Dickson M, Montgomery D, and Wilson A. (2009): Genetic association of the major histocompatibility complex with rheumatoid arthritis implicates two non-DRB1 loci. Arthritis Rheum, 60:53-62.

24. Yang L, Maric I, McCloskey E, Eastell R. (2008): Shape, structural properties, and cortical stability along the femoral neck: a study using clinical QCT. J Clin Densitom, 11:373-382.

25. Yang L, Peel N, Clowes J, McCloskey E, Eastell R. (2009): Use of DXA-based structural engineering models of the proximal femur to discriminate hip fracture. J Bone Miner Res, 24:33-42.

Publications from 2006-2007

1. Beard J. (2007): Assessment of surgical competence Br J Surgery, 94:1315–6

2. Greetham D, Ellis C, Mewar D, Fearon U, Ultaigh S, Veale D, Guesdon F and Wilson A. (2007): Functional characterization of NF-kB inhibitor-like protein 1 (NFkBIL1), a candidate susceptibility gene for rheumatoid arthritis. Hum Mo. Genet, 16:3027-36.

3. Marinou I, Healy J, Mewar D, Moore D, Dickson M, Binks M, Montgomery D, Walters K and Wilson A. (2007): Association of interleukin-6 and interleukin-10 genotypes with radiographic damage in rheumatoid arthritis is dependent on autoantibody status. Arthritis Rheum, 56:2549-56.

4. Marinou I, Montgomery D, Dickson M, Binks M, Moore D, Bax D and Wilson A. (2007): The Interferon-induced helicase domain 1 A946G polymorphism is not associated with rheumatoid arthritis. Arthritis Res Ther, 9:R40.

5. Mewar D, Coote A, Moore D, Marinou I, Keyworth J, Dickson M, Montgomery D, Binks M and Wilson A. (2006): Independent associations of anti-cyclical citrullinated peptide antibodies and rheumatoid factor with radiographic severity of rheumatoid arthritis. Arthritis Res Ther, 8:R128.

6. Mewar D, Marinou I, Lee M, Timms J, Kilding R, Teare M, Read R and Wilson A. (2006): Haplotype-specific gene expression profiles in a telomeric major histocompatibility complex gene cluster and susceptibility to autoimmune diseases. Genes Immun, 7:625-31.

7. Thomson W, Barton A, Ke X, Eyre S, Hinks A, Bowes J, Donn R, Symmons D, Hider S, Bruce I, Wilson A, Marinou I, Morgan A, Emery P, Carter A, Steer S, Hocking L, Reid D, Wordsworth P, Harrison P, Strachan D and Worthington J. (2007): Rheumatoid arth ritis association at 6q23. Nat Genet, 39:1431-3.