Professor Ian Douglas (BSc, PhD, ILTM)
Tel: 0114 271 7957
Fax: 0114 271 7894
Email: i.douglas@sheffield.ac.uk
School Administrative Roles
Deputy Dean
Sub-theme leader (Medical Microbiology) for the Human Disease theme of the BDS course
Chair of Hygiene and Therapy Course Working Party
University Administrative Roles
Head of the Graduate School, Faculty of Medicine, Dentistry and Health
Member of the Doctoral and Researcher Development Committee
National Administrative Role
Editorial Advisory Board of Archives of Oral Biology
Research Interests
Methods of detecting infection in epithelium and the development of sensors for specific bacteria in such situations as periodontitis
The mechanisms of interaction of bacteria with epithelial cells including invasion
Pathogenic mechanisms of oral streptococci in infective endocarditis.
Interactions between oral streptococci and salivary components, with a view to understanding how they influence the ecology of oral bacteria.
Recently Published Papers
Zheng X, Cook JP, Watkinson M, Yang S, Douglas I, Rawlinson A, Krause S. Generic protease detection technology for monitoring periodontal disease. Faraday discussion 2011; 149: 37-47
Roy S, Honma K, Douglas I, Sharma A, Stafford G. Role of sialidase in glycoprotein utilisation by Tannerella forsythia. Microbiology. 2011; 157: 3195-202
Sarker P, Shepherd J, Swindells K, Douglas CWI, MacNeil S, Swanson L, Rimmer S. Highly-branched polymers with polymyxin end groups responsive to Pseudomonas aeruginosa. Biomacromolecules. 2011; 12: 1-5
Pham TK, Roy S, Noirel J, Douglas I, Wright PC2 , Stafford GP. A quantitative proteomic analysis of biofilm adaptation by the periodontal pathogen Tannerella forsythia. Proteomics 2010; 108: 1246-1251.
Suwannakul S, Stafford GP, Whawell SA, Douglas CWI. Identification of bistable populations of Porphyromonas gingivalis that differ in epithelial cell invasion. Microbiology 2010, 156: 3052-3064
Shepherd J, Sarker P; Rimmer S; Swanson L; MacNeil S; Douglas I. Hyperbranched poly(NIPAM) polymers modified with antibiotics for the reduction of bacterial burden in infected human tissue engineered skin. Biomaterials 2010; 32: 258-267.
Roy S, Douglas CWI, Stafford GP. A novel sialic acid utilisation and uptake system in the periodontal pathogen Tannerella forsythia. J Bacteriol 2010; 192: 2285-2293.
Shepherd J, Sarker P, Swindells K, Douglas I, MacNeil S, Swanson L, Rimmer S.Binding Bacteria to highly branched poly(N-isopropyl acrylamide) modified with vancomycin induces the coil-to-globule transition. J Am Chem Soc. 2010, 132, 1736–1737
Bingle L, Barnes FA, Lunn H, Musa M, Webster S, Douglas CWI, Cross SS, High AS, Bingle CD. Characterisation and expression of SPLUNC2, the human orthologue of rodent parotid secretory protein. Histochem Cell Biol. 2009; 132: 339-349.
Bertal K, Shepherd J, Douglas CWI, Madsen J, Armes S, Lewis A, MacNeil S. Antimicrobial activity of novel biocompatible wound dressings based on triblock copolymer hydrogels. J Mat Sci 2009; 44; 6233-6246
Links
www.sheffield.ac.uk/dentalschool/research/groups/ibio/hub
Research Students
Abigail Rice
Robert Ridley