David James: Publications
Selected Recent Publications
Galbraith DJ, Tait AS, Racher AJ, Birch JR, James DC
Control of culture environment for improved polyethylenimine-mediated transient production of recombinant monoclonal antibodies by CHO cells.
Biotechnology Progress 22 (3): 753-762.
(2006)
Dinnis DM, Stansfield SH, Schlatter S, Smales CM, Alete DE, Birch JR, Racher AJ, Marshall CT, Nielsen LK, James DC
Functional proteomic analysis of GS-NS0 murine myeloma cell lines with varying recombinant monoclonal antibody production rate.
Biotechnology and Bioengineering 94 (5): 830-841.
(2006)
Hodonicsky J, Zhang Y, James DC
Control of recombinant monoclonal antibody effector functions by Fc N-glycan remodeling in vitro.
Biotechnology Progress 21: 1644-1652.
(2005)
Bailey MJ, Hooker AD, Adams CS, Zhang S, James DC
An integrated analytical platform for high-throughput and rapid molecular characterization of recombinant monoclonal antibodies.
Journal of Chromatography B. Biomedical Applications. 826: 177-187.
(2005)
Dinnis DM, James DC
Engineering recombinant monoclonal antibody production by mammalian cells – lessons from nature.
Biotechnology and Bioengineering 91(2) 180-189.
(2005)
Schlatter, S, Stansfield SH, Dinnis DM, Racher AJ, Birch JR, James DC
On the optimal ratio of heavy to light chain genes for efficient monoclonal antibody production by mammalian cells.
Biotechnology Progress 21 (1): 122-133.
(2005)
Tait AS, Brown CJ, Galbraith DJ, Hines MJ, Hoare M, Birch JR, James DC
Transient production of recombinant proteins by chinese hamster ovary cells using polyethyleneimine/DNA complexes in combination with microtubule disrupting anti-mitotic agents.
Biotechnology and Bioengineering 88 (6): 707-721.
(2004)
Smales CM*, Dinnis DM*, Stansfield SH*, Alete D, Sage EA, Birch JR, Racher AJ, Marshall CT, James DC
Comparative proteomic analysis of GS NS0 murine myeloma cell lines with varying recombinant monoclonal antibody production rate.
Biotechnology and Bioengineering 88(4): 474-488.
(2004)
Underhill MF, Coley C, Birch JR, Findlay A, Kallmeier R, Proud CG, James DC
Engineering mRNA translation initiation to enhance transient gene expression in chinese hamster ovary cells.
Biotechnology Progress 19 (1): 121-129.
(2003)
Baker KN, Rendall MH, Patel A, Boyd P, Hoare M, Freedman RB, James DC
Rapid monitoring of recombinant protein products: a comparison of different technologies.
Trends in Biotechnology 20(4): 149-156.
(2002)
Smales CM, Pepper DS, James DC
Protein modification during anti-viral heat treatment bioprocessing of Factor VIII, Factor IX concentrates and model proteins in the presence of sucrose.
Biotechnology and Bioengineering 77 (1): 37-48.
(2002)
Hills AE, Patel A, Boyd P, James DC
Metabolic control of recombinant monoclonal antibody N-glycosylation in GS-NS0 cells.
Biotechnology and Bioengineering 75: 239-251.
(2001)
Smales CM, Pepper DS, James DC
Protein modifications during anti-viral heat bioprocessing and subsequent storage.
Biotechnology Progress. 17: 974-978.
(2001)
Davis PJ, Smales CM, James DC
How can thermal processing modify the antigenicity of proteins?
Allergy 56, 56-60.
(2001)
Baker KN, Rendall MH, Hoare M, Freedman RB, James DC
Metabolic control of recombinant protein N-glycosylation in Chinese hamster ovary and NS0 murine myeloma cells.
Biotechnology and Bioengineering 73: 188-202.
(2001)
Recent Invited, Plenary or Keynote Lectures
Engineering Foundation: Cell Culture Engineering X, Whistler, 2006
IBC Cell Line Engineering and Development, Zurich, 2006
Dechema, German Association of Biotechnology Companies, Munich, 2006
Society for Industrial Microbiology, Baltimore, 2006
Cambridge Antibody Technology, Cambridge, 2006
