The University of Sheffield
Chemical and Biological Engineering

Dr Jagroop Pandhal

Post Doctoral Research Associate
Biological and Environmental Systems Group

Tel: +44 (0)114 222 7631

email : j.pandhal@sheffield.ac.uk

My previous project was aimed at developing and applying proteomic tools for understanding adaptation in environmentally significant organisms. This led to the characterisation of the salt stress response of a
tentatively new species of cyanobacteria, isolated from a salt lake in the Sahara.

 

Check out the Podcast

http://www.wiley-vch.de/vch/journals/2120/podcast/podcast.xml

In addition, I examined the highly abundant and relatively newly discovered marine cyanobacterium, Prochlorococcus.

Presently I am utilising these tools as well as transcriptomics in another field. The recent discovery of a post-translational modification pathway in a bacterium has opened the possibility of using bacterial hosts for the production of therapeutic proteins. My project aims to use inverse metabolic engineering to examine the fitness for growth of E.coli cells which have been transformed with the appropriate modification machinery and modified protein.