Professor David Strutt: Publications
Thomas C, Strutt D.
The roles of the cadherins Fat and Dachsous in planar polarity specification in Drosophila.
Dev Dyn. 2012 241:27-39.
Goodrich LV, Strutt D.
Principles of planar polarity in animal development.
Development. 2011 138:1877-92. Review.
Strutt H, Warrington SJ, Strutt D.
Dynamics of core planar polarity protein turnover and stable assembly into discrete membrane subdomains.
Dev Cell. 2011 Apr 19;20(4):511-25.
Strutt D, Vincent JP.
Frizzled signaling: Gαo and Rab5 at the crossroads of the canonical and PCP pathways?
Sci Signal. 2010 3:pe43.
Brittle AL, Repiso A, Casal J, Lawrence PA, Strutt D.
Four-jointed modulates growth and planar polarity by reducing the affinity of dachsous for fat.
Curr Biol. 2010 May 11;20(9):803-10.
Strutt D.
Gradients and the specification of planar polarity in the insect cuticle.
Cold Spring Harb Perspect Biol. 2009 Nov;1(5):a000489.
Strutt H, Strutt D.
Asymmetric localisation of planar polarity proteins: Mechanisms and consequences.
Semin Cell Dev Biol. 2009 Oct;20(8):957-63. Epub 2009 Mar 21. Review.
Strutt D.
The planar polarity pathway.
Curr Biol. 2008;18(19):R898-902.
Strutt H, Strutt D.
Differential stability of flamingo protein complexes underlies the establishment of planar polarity.
Curr Biol. 2008;18(20):1555-64.
Strutt D, Warrington SJ.
Planar polarity genes in the Drosophila wing regulate the localisation of the FH3-domain protein Multiple Wing Hairs to control the site of hair production.
Development. 2008;135(18):3103-11.
Brunk K, Vernay B, Griffith E, Reynolds NL, Strutt D, Ingham PW, Jackson AP.
Microcephalin coordinates mitosis in the syncytial Drosophila embryo.
J Cell Sci. 2007;120(Pt 20):3578-88.
Bastock, R. and Strutt, D.
The planar polarity pathway promotes coordinated cell migration during Drosophila oogenesis.
Development 2007; 134:3055-3064.
Strutt, D. and Strutt, H.
Differential activities of the core planar polarity proteins during Drosophila wing patterning.
Developmental Biology 2007; 302:181-194.
Strutt, H., Price, M.A., and Strutt, D.
Planar polarity is positively regulated by casein kinase I epsilon in Drosophila.
Current Biology 2006; 16:1329-1336.
Shimada Y, Yonemura S, Ohkura H, Strutt D, Uemura T.
Polarized transport of frizzled along the planar microtubule arrays in
drosophila wing epithelium.
Dev Cell. 2006;10(2):209-22.
Strutt H, Strutt D.
Long-range coordination of planar polarity in Drosophila.
Bioessays. 2005 Dec;27(12):1218-27. Review.
Strutt D
Organ shape: controlling oriented cell division.
Curr Biol. 2005 Sep 20;15(18):R758-9. Review.
Strutt D.
Mathematical modeling of planar polarity.
Dev Cell. 2005 Feb;8(2):134-6.
Strutt, H, Mundy, J, Hosfstra, K and Strutt, D
Cleavage and secretion is not required for Four-jointed function in Drosophila patterning.
Development 2004; 131:881-890
Strutt D
Frizzled signalling and cell polarisation in Drosophila and vertebrates.
Development. 2003;130(19):4501-13. Review.
Strutt, H and Strutt, D
EGF signalling and ommatidial rotation in the Drosophila eye.
Current Biology 2003; 13:1451-1457
Bastock, R, Strutt, H and Strutt, D
Strabismus is asymmetrically localised and binds to Prickle and Dishevelled during Drosophila planar polarity patterning.
Development 2003; 130:3007-3014
Strutt H and Strutt D
Nonautonomous planar polarity patterning in Drosophila: Dishevelled-independent functions of frizzled.
Developmental Cell 2002; 3:851-863
Strutt D, Johnson R, Cooper K, Bray S
Asymmetric localization of frizzled and the determination of notch-dependent cell fate in the Drosophila eye.
Curr Biol. 2002; 12(10):813-24
Strutt H, Strutt D.
Planar polarity: photoreceptors on a high fat diet.
Curr Biol. 2002;12(11):R384-5. Review.
Strutt DI
Asymmetric localization of frizzled and the establishment of cell polarity in the Drosophila wing.
Mol Cell. 2002; 7(2):367-7
Strutt DI. (2002)
The asymmetric subcellular localisation of components of the planar polarity pathway.
Semin Cell Dev Biol. 13(3):225-31
Strutt D.
Planar polarity: getting ready to ROCK.
Curr Biol. 2001 Jul 10;11(13):R506-9.
Zeidler MP, Perrimon N and Strutt DI
Multiple rôles for four-jointed in planar polarity and limb patterning.
Dev Biol. 2000; 228:181-196
Fanto M, Weber U, Strutt DI and Mlodzik M
Nuclear signaling by Rac and Rho GTPases is required in the establishment of epithelial planar polarity in the Drosophila eye.
Curr Biol. 2000; 10:979-88
Strutt H and Strutt D.
Polarity determination in the Drosophila eye.
Curr Opin Genet Dev. 1999; 9:442-446
Zeidler MP, Perrimon N and Strutt DI
The four-jointed gene is required in the Drosophila eye for ommatidial polarity specification.
Curr Biol. 1999; 9:1363-72
Zeidler MP, Perrimon N and Strutt DI.
Polarity determination in the Drosophila eye: a novel rôle for unpaired and JAK/STAT signaling.
Genes Dev. 1999; 13:1342-53
Boutros M, Paricio N, Strutt DI and Mlodzik M
Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling.
Cell 1998; 94:109-118
Strutt DI and Mlodzik M
Hedgehog is an indirect regulator of morphogenetic furrow progression in the Drosophila eye disc.
Development 1997; 124:3233-3240
Strutt DI, Weber U and Mlodzik M
The rôle of RhoA in tissue polarity and Frizzled signalling.
Nature 1997; 387:292-295
Strutt DI and Mlodzik M
The regulation of hedgehog and decapentaplegic during Drosophila eye imaginal disc development.
Mech Dev. 1996; 58:39-50
Strutt DI and Mlodzik M
Ommatidial polarity in the Drosophila eye is determined by the direction of furrow progression and local interactions.
Development 1995; 121:4247-4256
Strutt DI, Wiersdorff V and Mlodzik M
Regulation of furrow progression in the Drosophila eye by cAMP-dependent protein kinase A.
Nature 1995; 373:705-709