Dr Penny Rashbass
Department of Biomedical Science
The University of Sheffield
Western Bank
Sheffield S10 2TN
United Kingdom
Senior Lecturer
Room: D225 Alfred Denny building
Telephone: +44 (0) 114 222 2382
email : p.rashbass@sheffield.ac.uk
Career history
- 2003-present: Senior Lecturer, University of Sheffield
- 1998-2003 Lister Research Fellow, MRC Human Genetics Unit, Edinburgh + University of Sheffield
- 1994-1997: MRC Clinical Training Fellow-MRC Human Genetics Unit-Research Advisor Prof. Veronica van Heyningen - Clinical commitment - Paediatric Oncology – Royal Hospital for Sick Children Edinburgh
- 1993-1994: Senior House Officer- Royal Hospitals for Sick Children in Glasgow + Edinburgh
- 1989-1993: PhD – Developmental Biology – ICRF Developmental Biology Unit, Oxford + Centre for Genome Research, Edinburgh – supervisor Dr Rosa Beddington
- 1988-1989 House Officer, The London Hospital + Newham District General Hospital
- 1985-1988 MB BChir The London Hospital (degree from Cambridge University)
- 1982-1985 BA Hons. Medical Science - Cambridge University
Research interests
Sheets of epithelial cells (also known as epithelia) line the body surface and all body cavities As the environment on each side of the cell is different, perhaps it is not surprising that in order for epithelia to develop and function correctly, cellular proteins need to be asymmetrically localized within the cell. Abnormalities in this "apical-basal" polarity results in a range of disorders including cancer and retinal degeneration. The Rashbass lab studies the role of some of the key apical-basal polarity regulators in development and disease
Read more on research in the Rashbass laboratory
Activities and distinctions
- 2008-2012 member of EU framework VII consortium "Crumbs insight"
- 2007-2010 BBSRC Genes & Developmental Biology committee member
- 2002-2005: member of EU framework V consortium 'Crumbs therapeutics'
- BBSRC Review of Computational Requirements Working Group committee member
Funding
- BBSRC
- European Union FP5
- European Union FP7
- Lister Research Fellowship
- Wellcome Trust
- Yorkshire Cancer Research
Recent publications
Boroviak T, Rashbass P.
The apical polarity determinant Crumbs 2 is a novel regulator of ESC-derived neural progenitors.
Stem Cells. 2011 29(2):193-205. doi: 10.1002/stem.567.