Professor David Grundy
Professor of Biomedical Science
Head of Department
Department of Biomedical Science
The University of Sheffield
Western Bank
Sheffield S10 2TN
United Kingdom
Room: B103 Addison building
Telephone: +44 (0) 114 222 4657
Email : D.Grundy@sheffield.ac.uk
|
PA: Mrs S Harding |
Lab:- Room: E06a, Florey building Telephone: +44 (0) 114 222 4657 Fax: +44 (0) 114 2222360 |
Career history
- 2012 - Present: Head of Department, Biomedical Science
- 1999 - Present: Professor, Dept. of Biomedical Science, Sheffield
- 1998 - 2004: Germany Gästprofessor in the Department of Surgery, University of Tübingen, Germany
- 1996 - 1999: Reader, Dept. of Biomedical Science, Sheffield
- 1990 - 1996: Senior Lecturer, Dept. of Biomedical Science, Sheffield
- 1990: Visiting Scientist, University of Hohenheim, Germany
- 1988: Visiting Scientist, University of Western Australia, Perth
- 1987 - 1990: Wellcome Trust Senior Lecturer, Department of Biomedical Science, University of Sheffield
- 1981: Visiting Scientist, University of Calgary, Canada
- 1980 - 1987: Lecturer, Department of Physiology, University of Sheffield
- 1978 - 1980: Postdoctoral Research Fellow, Department of Physiology, University of Sheffield
Research interests
Neurogastroenterology – The Neural control of Gut function
Our research is focused on the neural control of gut function. The term "neurogastroenterology" has been coined to describe the field of brain-gut interactions. This field has under gone rapid expansion recently for a number of reasons.
Read more on research in the Grundy laboratory
Activities and distinctions
- Editor in Chief of the Journal of Neurogastroenterology and Motility. Chair of the journal management committee.
- Member of the Varenna group, an international educational organisation providing teaching material for gastroenterology.
- Visiting Professor St George’s University, Grenada (April 2007)
- Invitations to chair/speak at national and international meetings and advisory boards in 2006/7 including the plenary lecture at the International Neurogastroenterology Society meeting (Jeju, Korea), invited speaker at New Vistas on GI motility: from Physiology to Therapy (Rome), Invited speaker at the 15th United Euopean Gastroeneterology week (Paris). Flemish gastroenterology society (Antwerp). Member of a Novartis advisory board (New York).
Funding
- AstraZeneca
- Bardhan Trust
- Biotechnology and Biological Sciences Research Council (BBSRC)
- GlaxoSmithKline (GSK)
- Sheffield Hospital Charitable Trust
Recent publications
Bulmer DC, Grundy D.
Achieving translation in models of visceral pain.
Curr Opin Pharmacol. 2011 11:575-81.
Grundy D.
Stop press--neurogastroenterology and motility announce new editors.
Neurogastroenterol Motil. 2011 23:813.
Keating C, Pelegrin P, Martínez CM, Grundy D.
P2X7 receptor-dependent intestinal afferent hypersensitivity in a mouse model of postinfectious irritable bowel syndrome.
J Immunol. 2011 187:1467-74. Epub 2011 Jun 22.
Jiang W, Kirkup AJ, Grundy D.
Mast cells drive mesenteric afferent signalling during acute intestinal ischaemia.
J Physiol. 2011 589:3867-82. Epub 2011 Jun 13.
Daly DM, Collins VM, Chapple CR, Grundy D.
The afferent system and its role in lower urinary tract dysfunction.
Curr Opin Urol. 2011 21:268-74. Review.
Grundy D.
TRPs along the alimentary canal.
Pain. 2011 152:1443-4. Epub 2011 Apr 29.
Cremon C, Carini G, Wang B, Vasina V, Cogliandro RF, De Giorgio R, Stanghellini V, Grundy D, Tonini M, De Ponti F, Corinaldesi R, Barbara G.
Intestinal serotonin release, sensory neuron activation, and abdominal pain in irritable bowel syndrome.
Am J Gastroenterol. 2011 106:1290-8.
Donovan J, Grundy D.
The differential effect of CB1 receptors on the discharge of afferent and efferent fibres supplying the rat jejunum.
Neurogastroenterol Motil. 2011 23:567-e209.
Rong W, Kimura H, Grundy D.
The neurophysiology of hydrogen sulfide.
Inflamm Allergy Drug Targets. 2011 10:109-17. Review.
Lubbers T, de Haan JJ, Hadfoune M, Zabeau L, Tavernier J, Zhang Y, Grundy D, Greve JW, Buurman WA.
Chylomicron formation and glucagon-like peptide 1 receptor are involved in activation of the nutritional anti-inflammatory pathway.
J Nutr Biochem. 2011 22:1105-11. Epub 2011 Jan 15.