Dr Anne-Gaelle Borycki
Senior Lecturer
Department of Biomedical Science
The University of Sheffield
Western Bank
Sheffield S10 2TN
United Kingdom
Room: D232 Alfred Denny building
Telephone: +44 (0) 114 222 2701
Fax: (44) 114 276 5413
email : a.g.borycki@sheffield.ac.uk
Research interests
Somite and neural tube patterning by Sonic hedgehog signalling. The Borycki lab uses the vertebrate chick and mouse animal models to study how the morphogen signalling molecule Sonic Hedgehog and its effectors, the Gli transcription factors, specify somitic and neural progenitor cells during embryonic development.
Read more on research in the Borycki laboratory
Career history
- 2011-present: Senior Lecturer, Department of Biomedical Science
- 2000-2010: Lecturer, Department of Biomedical Science
- 1994-2000: Post-doctoral Fellow at the University of Pennsylvania Medical School in Philadelphia - USA (Advisor: Prof: Charles P. Emerson, Jr)
- 1992-1994: Post-doctoral Fellow at Gustave Roussy Institute for Cancer Research in Villejuif - France (Advisor: Dr. Serge A. Leibovitch)
- 1992: Ph.D in Molecular Biology from University of Science, Paris - France (Supervisor: Dr. Serge A. Leibovitch)
- 1987: M.Sc in Biochemistry from University of Science, Paris - France
- 1986: B.Sc. in Biochemistry from University of Science, Paris - France
Activities and distinctions
- Member of the EU-funded Network of Excellence "Cells into Organs"
- Member and Research Program coordinator of the EU-funded Network of Excellence "MYORES"
- Panel member since 2007, Muscle Biology Committee, AFM (Association Francaise contre les Myopathies)
Funding
- AFM (Association Francaise contre les Muopathies)
Recent publications
Borycki AG.
The myotomal basement membrane: Insight into laminin-111 function and its control by Sonic hedgehog signaling.
Cell Adh Migr. 2013 Jan 1;7: 72-81
Balczerski B, Zakaria S, Tucker AS, Borycki AG, Koyama E, Pacifici M, Francis-West P.
Distinct spatiotemporal roles of hedgehog signalling during chick and mouse cranial base and axial skeleton development.
Dev Biol. 2012 Nov 15;371(2):203-14.
Anderson C, Williams VC, Moyon B, Daubas P, Tajbakhsh S, Buckingham ME, Shiroishi T, Hughes SM, Borycki AG.
Sonic hedgehog acts cell-autonomously on muscle precursor cells to generate limb muscle diversity.
Genes Dev. 2012 Sep 15;26(18):2103-17.
Van Hateren NJ, Das RM, Hautbergue GM, Borycki AG, Placzek M, Wilson SA.
FatJ acts via the Hippo mediator Yap1 to restrict the size of neural progenitor cell pools.
Development. 2011 May;138(10):1893-1902.
Coy S, Caamaño JH, Carvajal J, Cleary ML, Borycki AG.
A Novel Gli3 Enhancer Controls the Gli3 Spatiotemporal Expression Pattern through a TALE Homeodomain Protein Binding Site.
Mol Cell Biol. 2011 Apr;31(7):1432-43
Coy SE, Borycki AG.
Expression analysis of TALE family transcription factors during avian development.
Dev Dyn. 2010 Apr;239(4):1234-45.
Anderson C, Thorsteinsdóttir S, Borycki AG.
Sonic hedgehog-dependent synthesis of laminin alpha1 controls basement membrane assembly in the myotome.
Development. 2009 Oct;136(20):3495-504.