Dr Patrik Nosil

Dr Patrik Nosil

Room B82, Alfred Denny Building
Tel: +44 (0)114 222 0089
Fax: +44 (0)114 222 0002
email: p.nosil@sheffield.ac.uk

Lab website: nosil-lab.group.shef.ac.uk/


  • BSc (1999) University of Victoria (Canada)
  • PhD (2006) Simon Fraser University (Canada)
  • Postdoctoral Fellow (2006-2008), University of British Columbia (Canada)
  • Academic Fellow (2008-2009), Institute for Advanced Study, Wissenschaftskolleg (Berlin, Germany)
  • Assistant Professor, University of Colorado, Boulder (2009-2011)
  • ERC funded Independent Research Fellow, University of Sheffield (2012-present)

Research Interests

Ecological and genomic basis of adaptation and speciation

Stick Insect

Research in the lab focuses on the evolutionary processes driving and constraining the formation of new species. In particular, we are interested in the role of adaptation to new ecological environments, via natural selection, in the speciation process. Related interests concern the impact of natural selection on genomic divergence, predator-prey interactions, eco-evolutionary dynamics and macro-evolutionary patterns of character evolution. Various data are used to address these topics, including field observations, manipulative field and lab experiments and next generation DNA sequencing data. The molecular work spans a range of sub-disciplines, including evolutionary genetics and population genomics. We also integrate these empirical studies with theoretical work and comparative analyses. Our main study system are Timema stick insects.

Current Research Group

Ph.D. Students

Aaron Comeault: Genomic basis of adaptation and speciation. Click HERE for his website.

Timothy Farkas: Eco-evolutionary dynamics and the ecological effects of evolution. Click HERE for his website.

Postdoctoral Fellows

Mortiz Muschick: Adaptive radiation. Click HERE for his website.

Victor Soria-Carrasco: Macro-evolution, computational biology.

Rûdiger (Rudy) Riesch: Animal communication and speciation. Click HERE for his website.

Recent Publications

Nosil, P. 2012 Ecological speciation. Oxford University Press, Oxford

Nosil, P. 2012 Degree of sympatry affects reinforcement in Drosophila. Evolution, in press

Crespi, B.J. and Nosil, P. 2012 Conflictual speciation: species formation via intragenomic conflict. Trends Ecol. Evol., in press

Nosil, P., Gompert, Z., Farkas, T., Comeault, A., Feder, J.L., Buerkle, C.A., Parchman, T.L. 2012 Genomic consequences of multiple speciation processes in a stick insect. Proc. R. Soc. Lond. B. 279: 5058-5065

Feder, J.L., Egan, S.P., Nosil, P. 2012 The genomics of speciation-with-gene-flow. Trends Genet. 28: 342-350

Feder, J.L., Gejii, R., Yeaman, S., Nosil, P. 2012 Establishment of new mutations under divergence and genome hitchhiking. Phil. Trans. R. Soc. Lond. B. 367:461-474

Feder, J.L., Gejii, R., Powell, T.H.Q., Nosil, P. 2011 Adaptive chromosomal divergence driven by mixed geographic mode of evolution. Evolution 65: 2157-2170

Nosil, P. and Schluter, D. 2011 The genes underlying the process of speciation. Trends Ecol. Evol. 26: 160-167

Nosil, P. and Flaxman, S. 2011 Conditions for mutation-order speciation. Proc. R. Soc. Lond. B. 278: 399-407

Servedio, M.R., Van Doorn, G.S., Kopp, M., Frame, A.M., Nosil, P. 2011 Magic traits in speciation: 'magic' but not rare? Trends Ecol. Evol. 26: 389-397

Michel, A.P., Sim, S., Powell, T., Nosil, P., Feder, J.L. 2010 Widespread genomic divergence during sympatric speciation. Proc. Natl. Acad. Sci. USA 107: 9724-9729

Feder, J.L. and Nosil, P. 2010 The efficacy of divergence hitchhiking in generating genomic islands during ecological speciation. Evolution 64: 1729-1747

Nosil, P. 2009 Adaptive population divergence in cryptic color-pattern following a reduction in gene flow. Evolution 63: 1902-1912

Nosil, P., Funk, D.J., Ortiz-Barrientos, D. 2009 Divergent selection and heterogeneous genomic divergence. Mol. Ecol. 18: 375-402

Nosil, P., Egan, S.P., Funk, D.J. 2008 Heterogeneous genomic differentiation between walking-stick ecotypes: 'isolation by adaptation' and multiple roles for divergent selection. Evolution 62: 316-336

Nosil, P. 2007 Divergent host-plant adaptation and reproductive isolation between ecotypes of Timema cristinae. Am. Nat. 169: 151-162

Nosil, P. and Crespi, B.J. 2006 Experimental evidence that predation promotes divergence during adaptive radiation. Proc. Natl. Acad. Sci. USA 103: 9090-9095

Funk, D.J., Nosil, P., Etges, B. 2006 Ecological divergence exhibits consistently positive associations with reproductive isolation across disperate taxa. Proc. Natl. Acad. Sci. USA 103: 3209-3213

Nosil, P., and Mooers, A. 2005 Testing hypotheses about ecological specialization using phylogenetic trees. Evolution 59: 2256-2263

Nosil, P., Vines, T., Funk, D.J. 2005 Perspective: Reproductive isolation caused by natural selection against immigrants from divergent habitats. Evolution 59: 705-719

Rundle, H. and Nosil, P. 2005 Ecological speciation. Ecol. Letters 8: 336-352

Nosil, P., Crespi, B.J., Sandoval, C.P. 2003 Reproductive isolation driven by the combined effects of ecological adaptation and reinforcement. Proc. R. Soc. Lond. B. 270: 1911-1918

Nosil, P., Crespi, B.J., Sandoval, C.P. 2002 Host-plant adaptation drives the parallel evolution of reproductive isolation. Nature 417: 440-443